COMPARATIVE STUDIES ON HEPATIC N- AND O-DEMETHYLATION
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概要
- 論文の詳細を見る
Oxidative dealkylation is an important step in the metabolism of various foreign compounds including a number of clinically useful drugs (1). Studies to establish a comparison between aromatic hydroxylation of aniline and side chain hydroxylation at methyl moiety of <I>p</I>-nitrotoluene (2) are further extended in the present report to other types of microsomal oxidative reactions, i.e., N- and O-demethylation, the two possible variations of hydroxylation (1).
- 社団法人 日本薬理学会の論文
著者
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Ikeda Masayuki
Department Of Physics Aoyama-gakuin University
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IMAMURA Toshiko
Department of Public Health, Faculty of Medicine, Kyoto University
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OHTSUJI Hatsue
Saku General Hospital
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Ikeda Masayuki
Department Of Environmental Health Tohoku University School Of Medicine
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IKEDA Masayuki
Department of Public Health, Faculty of Medicine, Kyoto University
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