INCORPORATION OF <SUP>32</SUP>P INTO PHOSPHOLIPIDS OF THE ADRENAL MEDULLA DURING AND AFTER STIMULATION BY SECRETOGOGUES
スポンサーリンク
概要
- 論文の詳細を見る
It has been shown that there was a marked increase in the incorporation of <SUP>32</SUP>P into the phospholipid fraction when secretion of amines from the adrenal medulla (1, 2), enzyme from pancreas (3, 4) or the salivary gland (5, 6) and other substances from respective glands (7) were stimulated with cholinergic agents. From these striking phospholipid effects, it has been considered that phospholipids may play a role in the active secretion of proteins by exocrine glands and of amines by the adrenal medulla (7).<BR> However, as to the time courses of acetylcholine-stimulated <SUP>32</SUP>P incorporation into phospholipids of the adrenal medulla, and of acetylcholine-evoked amine release, it was observed that amine release reached a maximum after 10 min; in contrast <SUP>32</SUP>P incorporation into phospholipids became apparent only after this interval of time (2). Furthermore, calcium ion had little influence on stimulating phospholipid effects of acetylcholine in the adrenal medulla (8) or pancreas slices (4), while their secretions in response to acetylcholine were completely inhibited by omission of calcium. Another possible role of the increased phospholipid metabolism might be involved in a post-process of chromafiin cells after the stimulated secretion.<BR> The present work represents efforts to trace the role of phospholipid metabolism of the adrenal medulla in reference to the possible “recovery process” of the tissue after the stimulated secretion.
- 社団法人 日本薬理学会の論文
著者
-
Yamamoto Iwao
Department Of Functional Polymer Science Faculty Of Textile Science And Technology Shinshu Universit
-
IWATSUBO Katsuya
Department of Pharmacology, Osaka University Dental School
-
ODANAKA Takeshi
Department of Pharmacology, Osaka University Dental School
-
YAMAMOTO Iwao
Department of Pharmacology, Osaka University Dental School
-
IWATSUBO Katsuya
Department of Pharmacology, Faculty of Dentistry, Osaka University
-
Yamamoto Iwao
Department of Chemistry, Shinshu University at Ueda
関連論文
- Relationship between Balance Performance and Leg Muscle Strength in Elite and Non-Elite Junior Speed Skaters
- Effect of Ageing on Quadriceps Muscle Strength and on the Forward Shift of Center of Pressure during Sit-to-stand Movement from a Chair
- Y-931, a Novel Atypical Antipsychotic Drug, Is Less Sensitive to Oxidative Phenomena
- Effect of Bite with and without Dentures on Soleus H-Reflex in the Elderly
- Sagittal Kinematics and Muscular Activities of Torso and Hip during Trunk Flexion and Extension
- The Influence of Thermotherapy on Muscle Elasticity : Measurement of Pennation Angle with the Use of Ultrasound Images
- EFFECT OF SODIUM ION ON LEVELS OF CYCLIC ADENOSINE 3, 5-MONOPHOSPHATE IN GUINEA PIG CEREBRAL SLICES
- ACTION OF TYRAMINE ON THE SALIVARY AMYLASE SECRETION FROM RABBIT PAROTID GLAND IN REFERENCE TO THAT OF NICOTINE
- Synthesis of 1-Nonene from Decanoic Acid by Polymer-Bound Palladium Complexes
- Participation of Opiate and Serotonergic Systems in Brain Conditioning Stimulation in the Inhibition of the Potentials Evoked by Tooth Pulp Stimulation in the Pars Caudalis of the Trigeminal Sensory Nucleus of the Rat
- INCORPORATION OF 32P INTO PHOSPHOLIPIDS OF THE ADRENAL MEDULLA DURING AND AFTER STIMULATION BY SECRETOGOGUES
- EFFECT OF MORPHINE ON DOPAMINE-SENSITIVE ADENYLATE CYCLASE ACTIVITY OF NUCLEUS ACCUMBENS
- Effect of neuroactive peptides on labeled 5-hydroxytryptamine release from rat spinal slices in vitro.
- PHARMACOLOGICAL EVALUATIONS OF BIS-β-CHLOROETHYLAMINE COMPOUNDS
- PHARMACOLOGICAL STUDIES ON NITROGEN MUSTARD-N-OXIDES
- EFFECTS OF NITROMIN, MITOMYCIN C AND CHROMOMYCIN A3 ON THE TESTIS AND HEMATOPOIETIC ORGAN IN MICE AND RATS
- Molecular structures of adducts of benzoyl isothiocyanate and hydrazones determined by the X-ray diffraction method.
- EFFECT OF CHLORPROMAZINE ON ENZYMIC REACTIONS INVOLVING METAL IONS
- CATECHOLAMINE SECRETION FROM THE ADRENAL GLAND TREATED WITH NEURAMINIDASE, PROTAMINE OR ALKYLATING AGENT
- A NOTE ON cis-UROCANIC ACID