Participation of the nucleus reticularis gigantocellularis in the morphine-induced elevation of plasma corticosterone in rats.
スポンサーリンク
概要
- 論文の詳細を見る
The effects of morphine, adrenocorticotropic hormone (ACTH) and formalin on plasma corticosterone levels were investigated in the nucleus reticularis gigantocellularis (NRGC)-lesioned rats. ACTH (1.0 U/kg) or formalin (6.4%, 0.2 ml/rat) elevated plasma corticosterone in both sham-lesioned and NRGC-lesioned rats at the same degree, while morphine (10 mg/kg) also elevated plasma corticosterone in sham-lesioned rats, the elevation of which was significantly reduced by NRGC-lesioning. These findings suggest that the NRGC is involved in the corticosterone-increasing effect of morphine, but not involved in the effect of ACTH or formalin.
- 公益社団法人 日本薬理学会の論文
著者
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Ozaki Masanobu
Department Of Cardiology Fukuoka University School Of Medicine
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Kishioka Shiroh
Department Of Pharmacology Wakayama Medical College
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Yamamoto Hiroyuki
Department Of Applied Biology Faculty Of Textile Science And Technology Shinshu University
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Kishioka Shiroh
Department of Pharmacology, Wakayama Medical College
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TAMURA Sadako
Department of Pharmacology, Wakayama Medical College
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IGUCHI Yoshiyuki
Department of Pharmacology, Wakayama Medical College
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