Developmental change in calcitonin secretory capacity of fetal rat thyroid C-cells.
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概要
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Developmental changes in calcitonin (CT) secretory capacity of C-cells were studied by using primary cultures prepared from the thyroid glands of rat fetuses at 1 6th, 1 8th and 20th day of gestation and the thyroid glands of 28-day-old rats. Both CT content of C-cells and high Ca<SUP>2+</SUP>-stimulated CT secretion increased with the age of the rats. The ratio of secreted CT to the CT content of C-cells also increased according to the age. These results demonstrated the functional development of C-cells during the fetal period.
- 公益社団法人 日本薬理学会の論文
著者
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Fujii Tomoko
Department Of Biology School Of Education Waseda University
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NISHIYAMA Ichiro
Department of Pharmacology, Teikyo University School of Medicine
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