アルコールの眼運動系に及ぼす影響

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It is known that alcohol affects the oculomoto system and elicits positionalacoholnystagmus Recently it has been shown that disturbance in smooth pursuit eye movements occurs depend-ing on the quantity of ingested alcohol.However, it is also known that test is normal at the early stage of alcohol-induced breakdown of smooth pursuit movements.This indicates that alcohol affects the cerebellum prior to affecting the midbrain and pons(WILKINSON et al., 1974).In order to further investigate the effect of alcohol on th cerebellum, subjects ingested alcohol(whisky)and their oculomotor function was tested.The followings are general findings obtained.1)Low blood-alcohol concentration causes slight disturbance in the caloric eye-tracking pattern and slight positional nystagmus is occasionally evident.2)As the blood-alcohol level increases, positional nystagmus becomes more apparent and the eye-tracking pattern begins to break down.The caloric eye-trackingpa ttern be-comes severely disturbed.3)Gaze nystagmus does not appear until the blood-alcohol level becomesmuch higher.hese findings indicate that alcohol affects the caloric eye-tracking patterns prior to the conventional eye-tracking patterns.Alcohol must therefore initially affect the areas of the cerebellum related tovisual suppression, namely the flocculo-nodular system.
社団法人日本耳鼻咽喉科学会の論文