上喉頭神経内枝の再生後における病理組織所見

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Regeneration of, the internal branch of the superior laryngeal nerve was studied after the nerve was sectioned and immediately sutured. The nerve was sectioned and sutured lilaterally in five dogs in this experiment. Ten months after operation, longitudinal sections of the nerve including portion of the nerve suture and cross sections of the nerve 1em peripheral and central to the suture were prepared and stained by using the phosphotungstic acid hematoxylin method. Mucous membranes of the posterior wall of the larynx were also sectioned and stained by silver. As the results, each regenerative nerve formed a neuroma at the portion of the nerve sutured. In the nerve peripheral so the suture, remarkable proliferation of connective tissue surrounding each axon was recognized and decrease of the diameter of axons was observed. In the nerve central to the suture, only proliferation of connective tissue surrounding axon was observed. Moreover, the nerve ending fibers were observed in mucous membrane of the posterior wall of the larynx although these fibers seemed decreased in their number. These results lead us to the conclusion that the internal branch of the superior laryngeal nerve does not recover perfectly after this nerve was sectioned and then repaired immediately.
社団法人日本耳鼻咽喉科学会の論文