喉頭癌の臨床的研究喉頭癌の遺伝について

概要

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Carcinoma of the larynx in two brothers was reported. Their occupation was shoemaker and the pathology of the cancer was almost identical in two cases. The clinical and pathological findings were as fallows.The survey of familial incidence of the can-cer was conducted on 256 patients suffering from cancer of the larynx with following results.1) As the family history of the cases with cancer was retrospectively traced from the patient back to a family relation of the third degree, 88 cases of 256 cases (34%) were found to be cancerinflicted and 111 cases with cancer were noticed in total. 2) 58 cases in the first degree (parents and children), 35 cases in the second degree (brothers and grandparents) and 18 cases in the third degree (parents' siblings etc.).3) Among 111 cases, gastric cancer was 60 cases (54.0%), esophageal cancer, 11 cases (9.9%), cancer of uterus, 8 cases (7.2%), laryngeal cancer, 7 ca-ses (6.3%) and others were 25 cases (22.6%).
社団法人日本耳鼻咽喉科学会の論文