びまん浸潤型大腸癌20例の臨床病理学的検討

概要

論文の詳細を見る
Clinicopathologic characteristics of 20 patients, 11 men and 9 wemen with an average age of 64.9 (35-79), with primary diffusely infiltrating carcinoma of the colon and rectum were studied. The incidence of the lesions was 0.6% (20/3633) in our series of surgically resected carcinoma of the colon and. rectum. They located in the colon in 11 patients (C : 2, A : 1, T : 2, D : 1, S : 5) and in the rectum in 9. Alteration in bowel habit and abdominal distension were the most frequent symptoms. The histlogic types of the lesions were poorly differentiated adenocarcinoma in 9, signet-ring cell carcinoma in 5, well differentiated adenocarcinoma in 3 and moderately differentiated adenocarcinoma in 3. All lesions spread beyond the proper muscle with marked lymphatic permeation. The prognosis was vevry poor ; 18 patients in the present series died of the disease. All patients with poorly differentiated or signet-ring cell carcinoma died within 1 year after surgery. These lesions were classified histologically into two types, differentiated type and undifferentiated type. This classification was useful and revealed prognostic significance and histologic characteristics of the tumor.
日本大腸肛門病学会の論文