日本住血吸虫卵が介在した異時性多発早期大腸癌の1例

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Recently, cases of colorectal carcinoma associated with Shistosomisis Japonica are very rare. However, the relationship between the Ova and carainogenesis very interesting. We report a case of an early metachronous colon carcinoma associated with Ova of Shistosoma Japonicum.<BR>The patient was a 76-year-old man who had undergone sigmoidectomy for sigmoid colon carcinoma 7 years before. We found a IIa+IIc type early carcinoma in the ascending colon by a periodic colonofiber examinations. Ileocecal resection was carried out. The lesion of the carcinoma mesured macroscopically 0.7×0.6×0.2cm in size. The carcinoma slightly invaded into submucosal layer, and we found Ova of Shistosoma Japonicum in close proximity of the carcinoma. W e re-examined sections which were removed in initial operation, and found Ova in normal submucosal layer but no Ova was found in carcinomatous tissues.<BR>These findings sugested that the Ova might drop out with necrotic carcinoma tissue by cancer-growing.
日本大腸肛門病学会の論文