びまん浸潤型大腸癌の臨床病理学的検討

概要

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A clinicopathological study was done on 13 cases of diffusely infiltrating carcinoma of the large bowel. They were classfied into 2 groups based on their infiltration pattern as follows:<BR>1) Stromal type; the tops of infiltration of the cancer cells were shown in stroma.<BR>2) Lymph vessel type; the tops of infiltration of the cancer cells were only found in the lymph vessels.<BR>It is suggested that in the former type the lesion grows by the stromal infiltration and in the latter type lymph vessels infiltration.<BR>Comparing the 2 types, the stromal type is more frequently found in young women and its histological type was mucocellular adenocarcinoma, while the lymph vessel type is found more in older men and its histological type was poorly differentiated adenocarcinoma and muconodular adenocarcinoma. Macroscopically, the stromal type showed severe shrinkage and thickening of the wall, while the lympy vessel type showed weak shrinkage and its longitudinal diameter was longer. Lymph node metastasis of the lymph vessel type was marked and its prognosis was poor. By classifying diffusely infiltrafing carcinoma into 2 types, different clincopathological features were found, and the classification may be useful as the sub-typing of the diffusely infiltrating carcinoma of the large bowel.
日本大腸肛門病学会の論文