Lymphocyte Subsets in Muscle Biopsies of Human T-Lymphotropic Virus Type I Carriers with Polymyositis.
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概要
- 論文の詳細を見る
Recent epidemiologic studies have shown that human T-lymphotropic virus type I (HTLV-I) is associated with polymyositis. To clarify the histological features of HTLV-I positive polymyositis, we studied muscle tissue from two groups of patients with polymyositis, those seropositive for HTLV-I (5 patients) and those seronegative (5 patients). We examined the lymphocyte subsets in muscle biopsies using monoclonal antibodies. In the endomysium, a variable number of T-lymphocytes and macrophages and a smaller proportion of B-lymphocytes were found in both groups. In both HTLV-I positive and negative patients a variable number of T-lymphocytes and macrophages, with a smaller number of B-lymphocytes, were found in the perimysium. As a whole, the T-lymphocytes were predominantly of the helper/inducer phenotype in both groups. We failed to find any specific phenotype distribution among T-cells infiltrating the muscle of HTLV-I carriers with polymyositis.(Internal Medicine 31 : 973-977, 1992)
- 社団法人 日本内科学会の論文
著者
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HIGUCHI Itsuro
The Third Department of Internal Medicine, Faculty of Medicine,Kagoshima University
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FUKUNAGA HIDETOSHI
The Third Department of Internal Medicine, Faculty of Medicine, Kagoshima University
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Osame Mitsuhiro
The Third Department Of Internal Medicine Faculty Of Medicine
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IJICHI Toshiharu
the Third Department of Internal Medicine, Faculty of Medicine, Kagoshima University
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IZUMO Shuji
the Third Department of Internal Medicine, Faculty of Medicine, Kagoshima University
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HIGUCHI Itsuro
The Third Department of Internal Medicine, Faculty of Medicine, Kagoshima University
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