A Clinical Study of Adult Human Parvovirus B19 Infection
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概要
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Objective We investigated the clinical aspects of adult human parvovirus (HPV) B19 infection. Patients and Methods We retrospectively reviewed the charts of 21 consecutive patients [4 males, aged 32 to 43 years (average 38.0 years), and 17 females, aged 15 to 43 (average 34.2)] with adult HPV B19 infection who visited our outpatient department between July 1997 and June 1998. All diagnoses of adult HPV B19 infection were based on positive anti-HPV B19 IgM antibody in serum and/or positive HPV B19 DNA in peripheral blood. Results The predominant signs and symptoms of the patients were: fever (81.0%), arthralgia/myalgia (61.9%), skin rash (47.6%), general fatigue (42.9%), lymph node swelling (38.1%) and edema (38.1%). Six patients had the following underlying diseases or complications: pregnancy, myoma uteri, cervical cancer of the uterus, lupus diathesis/endometriosis, hereditary spherocytosis, and multiple sclerosis. The following abnormal laboratory findings (more or less than normal limits) were observed: anemia (81.0%), leukopenia (33.3%), elevated transaminases (28.6%), and elevated lactate dehydrogenase (LDH) (57.1%). Six patients were considered to have persistent infection. Conclusion HPV B19 can infect healthy adults and causes more predominant signs and symptoms (arthralgia, myalgia and fever) than in children, and adult HPV B19 infection can be suspected from the familial history and clinical findings. Accordingly, more attention must be paid to adult HPV B19 infection, particularly when erythema infectiosum is prevalent in children.(Internal Medicine 41: 295-299, 2002)
- 社団法人 日本内科学会の論文
著者
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OSAME Mitsuhiro
The Third Department of Internal Medicine, Faculty of Medicine,Kagoshima University
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Osame M
Departoment Of Neurology And Geriatrics Kagoshima University Graduate School Of Medical And Dental S
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Osame Mitsuhiro
The Third Department Of Internal Medicine Faculty Of Medicine Kagoshima University
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Osame Mitsuhiro
Department Of Medicine Kagoshima University Faculty Of Medicine
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Ozawa Masayuki
Department Of Biochemistry Faculty Of Medicne Kagoshima University
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Tara Mitsutoshi
Department Of Internal Medicine Kagoshima City Hospital
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HAYAKAWA Hitoshi
the Department of Internal Medicine, Kagoshima City Hospital
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TARA Mitsutoshi
the Department of Internal Medicine, Kagoshima City Hospital
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NIINA Kiyoshige
the Department of Internal Medicine, Kagoshima City Hospital
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Niina Kiyoshige
Department Of Internal Medicine Kagoshima City Hospital
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Hayakawa Hitoshi
The Department Of Internal Medicine Kagoshima City Hospital
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Osame Mitsuhiro
The Third Department Of Internal Medicine Faculty Of Medicine
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Osame Mitsuhiro
The Third Department Of Internal Medicine Kagoshima University
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Osame Mitsuhiro
The Third Department Of Internal Medicine Kagoshima University School Of Medicine Kagoshima
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