Catecholamine in Congestive Heart Failure (Report I)

概要

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In order to determine the role of the catecholamines in cardiac failure, we considered the urinary excretion of catecholamines on cardiac patients suffering from acquired valvular disease.Among those who were admitted to the ward of Kobe Medical College Hospital, 178 patients with the congestive cardiac failure were chosen. These patients have been divided into four groups according to the criteria of New York Heart Association. Values of both urinary adrenaline and noradrenaline were progressively increased from grade I to grade III of congestive heart failure and reduced in grade IV but not to the normal range.Urinary excretion of both adrenaline and noradrenaline had increased when the conditions were improved from grade IV to grade III and reduced with further restoration from grade III to grade II. When the conditions took a turn for the worse, urinary excretion of active catechols varied inversely.The measurements of urinary active catechols were made on every 5 or 6 hour urine during the course of the rapid digitalization and compared with some clinical features.Some comments were tried on the significance of urinary excretion of active catechols.
International Heart Journal刊行会の論文