The effects of isosorbide dinitrate on exercise-induced ST-segment elevation at the infarcted area in old myocardial infarction.

スポンサーリンク

概要

• 論文の詳細を見る

• To clarify the clinical significance and therapeutic implication of exercise-induced ST elevation at the infarcted area in old myocardial infarction (OMI), 30 patients with exercise-induced ST elevation underwent treadmill exercise testing. The patients with transient perfusion defects at the infarcted area on thallium-201 stress myocardial scintigraphy (group I:n=12) revealed a decreased rate of ST elevation expressed as ΔST/ΔHR×102 after 10mg of isosorbide dinitrate (ISDN), compared to the results of treadmill exercise testing under no medication (3.1±2.5 vs. 4.7±2.6, p<0.001). Exercise capacity and anginal threshold were improved after ISDN in group I. In contrast, the patients without transient perfusion defects (group II:n=18) revealed an increased rate of ST elevation after ISDN (2.4±1.1 vs. 2.0±0.8, p<0.05). It is concluded from the above results that if exercise-induced ST elevation at the infarcted area reflects transient myocardial ischemia, ISDN can decrease it by its antianginal effect. Additionally, treadmill exercise testing with ISDN is a useful means of clarifying the underlying pathophysiology and management in OMI cases with this effect on exercise-induced ST elevation at the infarcted area.

• International Heart Journal刊行会の論文

著者

• Fukuzaki Hisashi

  First Department Of Internal Medicine Kobe University

• KOBAYASHI Katsuya

  First Department of Internal Medicine, Kobe University School of Medicine

• TANIZAKI Toshiro

  First Department of Internal Medicine, Kobe University School of Medicine

関連論文

• -0271-MONOPHASIC ACTION POTENTIAL IN PATIENTS WITH TORSADES DE POINTES
• -75- COMPARISON OF DRUG EFFICACY AND INITIATION MODE OF VENTRICULAR TACHYCARDIA WITH OCCURRENCE SITUATION OF VENTRICULAR PREMATURE CONTRACTION : Arrhythmias : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 51th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCU
• -1128-PHOSPHATIDYLINOSITOL TURNOVER-INDUCED PROTEIN PHOSPHORYLATION IN HUMAN MONOCYTE-DERIVED MACROPHAGES STIMULATED BY NATIVE AND CHEMICALLY MODIFIED LDL : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• -0358-MECHANISM OF THE UPTAKE OF ASIALO LDL BY MACROPHAGES
• METABOLISM OF ASIALO-LDL IN HUMAN MONOCYTE-DERIVED MACROPHAGES : Arteriosclerosis : 53 Annual Scientific Meeting, Japanese Circulation Society
• PHOSPHATIDYLINOSITOL TURNOVER IN HUMAN MONOCYTE-DERIVED MACROPHAGES STIMULATED BY NATIVE AND CHEMICALLY MODIFIED LDL : Arteriosclerosis : 53 Annual Scientific Meeting, Japanese Circulation Society
• Arrhythmia in Young Patients with Mitral Valve Prolapse : THE 8TH CONFERENCE ON PRVENTION FOR RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE
• 5-HYDROXYTRYPTAMINE INDUCED PHOSPHOINOSITIDES HYDROLYSIS THROUGH 5-HT_2-RECEPTOR IN CULTURED FETAL MOUSE VENTRICULAR MYOCYTES : Myocardial Metabolism, Biochemistry : 53 Annual Scientific Meeting, Japanese Circulation Society
• -1175-RESTING THALLIUM-201 DELAYED IMAGES FOR ASSESSING VIAVILITY OF REGIONS WITH SEVERE WALL MOTION ABNORMALITY : COMPARISON OF WALL MOTION BEFORE AND AFTER REVASCULARIZATION : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• -0039-CONGESTIVE HEART FAILURE WITHOUT IMPAIRED LEFT VENTRICULAR FUNCTION IN AGED PATIENTS
• -P58-PREDICTIVE VALUE OF EARLY THALLIUM-201 AND TECHNETIUM-99M PYROPHOSPHATE SCANS FOR FUNCTIONAL OUTCOME AND PROGNOSIS IN ACUTE MYOCARDIAL INFARCTION : RI : FREE COMMUNICATIONS(III) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRC
• -411- ALTERATIONS IN ANTICOAGULANT PROTEINS, PROTEIN C AND ANTITHROMBIN III, IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION AND UNSTABLE ANGINA PECTORIS
• -261-THE SIGNIFICANCE OF EXERCISE THALLIUM-201 REDISTRIBUTION AFTER EARLY REPERFUSION IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION : COMPARISON BETWEEN ICT AND PTCA : Myocardial Infarction : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIF
• A Long-term Follow-up Study of Acute Myocarditis an Electrocardiographic and Echocardiographic Study : THE 8TH CONFERENCE ON PRVENTION FOR RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE
• A Long-term Follow-up Study of Acute Viral and Idiopathic Myocarditis : THE 7th CONFERENCE ON PREVENTION FOR RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE
• THE RELATIONSHIP BETWEEN CHANGES OF LATE POTENTIALS AND VENTRICULAR ARRHYTHMIAS IN ACUTE MYOCARDIAL INFARCTION : Arrhythmias (I) : FREE COMMUNICATIONS (II) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• CLINICAL SIGNIFICANCE OF LATE VENTRICULAR POTENTIALS IN VENTRICULAR TECHYCARDIA : Arrhythmias (II), Electrophysiology (II), Mapping : III : 48 Annual Scientific Meeting, Japanese Circulation Society
• RIGHT AND LEFT VENTRICULAR DIASTOLIC FILLING CHARACTERISTICS IN HYPERTROPHIC NON-OBSTRUCTIVE CARDIOMYOPATHY : Cardiac Function(I) : I : 48 Annual Scientific Meeting, Japanese Circulation Society
• STUDY OF TRANSESOPHAGEAL ATRIAL PACING TO ASSESS POSSIBILITY AND USEFULNESS IN CLINICAL USE : Arrhythmias (III) : V : 48 Annual Scientific Meeting, Japanese Circulation Society
• HEMATOMA OF THE INTERATRIAL SEPTUM ASSOCIATED WITH COMPLETE ATRIOVENTRICULAR BLOCK : The 53th Annual Scientific Session of the Japanese Circulation Society
• CLINICAL EVALUATION OF Tl-201 STRESS MYOCARDIAL SCINTIGRAPHY AND STRESS-INDUCED CHANGES IN PULMONARY Tl-201 ACTIVITY IN PATIENTS WITH OLD MYOCARDIAL INFARCTION : Radio isotope : FREE COMMUNICATIONS (Abstract) : 45 Annual Scientific Meeting, Japanese Circu
• -116-VASOCONSTRICTOR PROPERTIES OF SAPHENOUS VEIN AND INTERNAL MAMMARY ARTERY : Cardiovascular Drugs : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• THE CLINICAL AND PROGNOSTIC SIGNIFICANCE OF DIPYRIDAMOLE Tl-201 EMISSION COMPUTED TOMOGRAPHY IN PATIENTS WITH DILATED CARDIOMYOPATHY
• 9) TWO CASES OF HYPERTROPHIC CARDIOMYOPATHY (HCM) ASSOCIATED WITH LOCALIZED AKINESIS OF THE LEFT VENTRICULAR WALL SIMILAR TO MYOCARDIAL INFARCTION
• CHANGES OF SERUM TOTAL CHOLESTEROL AND TRIGLYCERIDE LEVELS IN NORMAL SUBJECTS IN JAPAN IN THE PAST TWENTY YEARS : Research Committee on Familial Hyperlipidemia in Japan
• Hemodynamic Effects of Digoxin on Congestive Heart Failure : PANEL DISCUSSION ON OPINIONS OF CARDIOTONIC DRUGS : 49th Annual Scientific Session of the Japanese Circulation Society
• Studies on the Preventive Method of Lowered Ventricular Fibrillation Threshold during Experimental Acute Myocardial Infarction : A Comparison between Disopyramide Phosphate and Lidocaine
• A Study on Myocardial Ischemia in the Left Ventricular Wall with Special Reference to Electrographic and Metabolic Changes
• Relationships between Red Cell Cation Contents and Blood Pressure Level
• Two Cases of Myocardial Infarction with Coronary Arteriovenous Fistula
• Coronary Collateral Circulation as an Important Factor to Modify the Ischemic Injury of the Myocardium in Coronary Ligated Dogs
• Effects of Ergonovine-Induced Vasoconstriction on the Genesis of Myocardial Ischemia during Coronary Stenosis in Dogs
• Beneficial Effects of the Coronary Collateral Circulation on Tachycardia-Induced Myocardial Ischemia during Experimental Coronary Stenosis
• Ventriculo-atrial Conduction in Patients with Normal and Impaired Atrio-ventricular Conduction
• Deleterious Effects of Vasodilating Agents : Induction of Subendocardial Ischemia in Dogs with Proximal Stenosis of Coronary Artery
• Exercise capacity correlating to exercise hemodynamics in coronary artery disease.
• Treatment of atrial flutter and rapid atrial tachycardia with transesophageal atrial pacing.
• Enhanced red cell sodium permeability in patients with borderline hypertension.
• Effects of diltiazem and nitroglycerin on left ventricular diastolic properties in patients with coronary artery disease.
• Effects of propranolol on coronary vasculature and cardiac performance in dogs with fixed and dynamic coronary stenosis.
• Noninvasive assessment of left ventricular diastolic filling in coronary artery disease by Doppler dipyridamole-stress testing.
• The role of myocarditis and myocardial fibrosis in dilated cardiomyopathy Analysis of 28 necropsy cases.:Analysis of 28 Necropsy Cases
• Impaired right ventricular filling in old myocardial infarction.
• Dilated cardiomyopathy an echocardiographic follow-up of 50 patients.
• Clinical and histopathologic correlation in patients with dilated cardiomyopathy. Value of force-velocity product.:Value of Force-Velocity Product
• Cardiac thrombus in dilated cardiomyopathy. Relationship between left ventricular pathophysiology and left ventricular thrombus.:Relationship between Left Ventricular Pathophysiology and Left Ventricular Thrombus
• The effects of isosorbide dinitrate on exercise-induced ST-segment elevation at the infarcted area in old myocardial infarction.
• Contractile responses of canine coronary collateral vessels.

もっと見る 閉じる

スポンサーリンク