Changes of Cardiac Performance in Renal Failure

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概要

• 論文の詳細を見る

• Clinical and experimental studies were carried out in order to evaluate the role of myocardial dysfunction in the genesis of circulatory congestion associated with renal failure.Among the patients with chronic renal failure, those with circulatory congestion had greater blood volume and higher venous pressure while lower cardiac index and stroke work index than those without circulatory congestion. After peritoneal dialysis, although blood volume and venous pressure decreased in both groups, cardiac index increased in the former while it decreased in the latter group. In 15 dogs, acute renal failure was produced by ligating both ureters. As uremia developed, blood volume and left ventricular end-diastolic pressure increased with or without an increase in cardiac index. The depression of ventricular function curve was evident in all the dogs. The peritoneal dialysis performed at this stage resulted in a prompt recovery of left ventricular end-diastolic pressure with minimum change in cardiac index. The measurement of dp/dt/IIT also indicated a depression of myocardial contractility at uremic stage and its recovery after dialysis.We conclude that impairment of myocardial function is implicated in the development of circulatory congestion in renal failure.

• International Heart Journal刊行会の論文

著者

• Uraoka Tadao

  The 2nd Department Of Internal Medicine Toyama Medical And Pharmaceutical University

• Uraoka Tadao

  1st Dept. Of Intern. Med. School Of Med. Kanazawa Univ.

• Inasaka Tohru

  First Department of Internal Medicine, School of Medicine, Kanazawa University

• Kaseno Kensuke

  First Department of Internal Medicine School of Medicine, Kanazawa University.

• Uraoka Tadao

  First Dept. of Intern. Med.. Kanazawa Univ. School of Med

• Kitagawa Shunsuke

  First Department of Internal Medicine, School of Medicine, Kanazawa University

• Takeuchi Jugoro

  First Department of Internal Medicine, School of Medicine, Kanazawa University

• Sugimoto Tsuneaki

  First Department Of Internal Medicine School Of Medicine Kanazawa University.

• HIRASAWA Kunihiko

  First Department of Internal Medicine, School of Medicine, Kanazawa University

• Uraoka Tadao

  The First Department Of Internal Medicine School Of Medicine Kanazawa University

• Inasaka Tohru

  First Department Of Internal Medicine School Of Medicine Kanazawa University.

• SUGIMOTO Tsuneaki

  First Department of Internal Medicine, School of Medicine, Kanazawa University

• KASENO Kensuke

  First Department of Internal Medicine, School of Medicine, Kanazawa University

• URAOKA Tadao

  First Department of Internal Medicine, School of Medicine, Kanazawa University

• TAKEUCHI Jugoro

  First Department of Internal Medicine, Kanazawa University School of Medicine

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