A Clinical Study of the Effect of Coenzyme Q on Congestive Heart Failure

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概要

• 論文の詳細を見る

• Expecting activation of myocardial energy liberation, coenzyme Q was applied as a treatment to 55 patients suffering from congestive heart failure. Daily doses of 50 to 100mg of coenzyme Q7 were injected intravenously in 21 cases for 3 to 35 days. Daily doses of 60mg of coenzyme Q7 were administered perorally in 17 cases for 14 to 196 days. Daily doses of 30mg of coenzyme Q10 were administered perorally in 17 cases for 7 to 182 days. Clinical effects were evaluated within 4 weeks by the criteria using a scoring method of severity of congestive heart failure which was devised by the authors. In summary a certain effect was found in 20 cases and a mild effect was observed in 29 cases. No significant changes were observed in heart rate and blood pressure. Exanthema appeared in 2 patients of the group of coenzyme Q7 intravenous injection. In conclusion the therapeutic effect of coenzyme Q was thought to be mild but stable in supplement to digitalis therapy in cases of congestive heart failure.

• International Heart Journal刊行会の論文

著者

• Ishiyama Taro

  National Senboku Hospital

• Yamamura Yuichi

  Third Department of Internal Medicine, Osaka University Medical School

• Wada Noboru

  Kobe Shosei Hospital

• Yamagami Toru

  The Center For Adult Diseases.

• Yamagami Toru

  The Center For Adult Diseases Osaka Department Of Cardiology

• Toyama Seiichi

  The Center For Adult Diseases

• ISHIYAMA Taro

  Third Dept. of Intern. Med., Osaka Univ. Med. School

• MORITA Yoshiharu

  Third Dept. of Intern. Med., Osaka Univ. Med. School

• Tsukamoto Nozomu

  Department of Intemal Medicine Nishinomiya,Municipal Central Hospital

• OHKUBO Masaaki

  Kobe Shosei Hospital

• ISHIYAMA Taro

  Third Department of Internal Medicine, Osaka University Medical School

• YAMAMURA YUICHI

  Third Department of Internal Medicine and Central Laboratory, Medical School of Osaka University

• YAMAGAMI Toru

  The Center for Adult Diseases

• MORITA Yoshiharu

  Third Department of Internal Medicine, Medical School of Osaka University

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