Increase of Hematocrit in Experimental Renal Hypertension and Its Reversal

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概要

• 論文の詳細を見る

• Hematocrit can be increased in experimental animals with renal hypertension of two-kidney type. The present study showed that the increased hematocrit was returned to normal by removal of the clipped kidney.The left renal artery was clipped in 13 rabbits with an intact contralateral kidney, and a sham operation was performed in 10 rabbits as a control. After an interval of 10 weeks the left kidney was removed in all animals. Blood pressure, hematocrit, hemoglobin content, and erythrocyte count were rapidly increased and remained raised after clipping of the renal artery but they did not show any significant changes after sham operation. A transient but significant increase of reticulocyte count was found at the end of the first week after clipping of the renal artery. Removal of the clipped kidney was followed by a rapid return of hematocrit, hemoglobin content, and erythrocyte count to normal within 2 weeks. Blood pressure was also decreased but not returned to normal by removal of the clipped kidney.

• International Heart Journal刊行会の論文

著者

• FUJII JUN

  3rd Department oflnternal Medicine. Faculty ofMedicine. University of Tokyo

• SEKI Akira

  The Institute for Adult Diseases Asahi Life Foundation

• Kuramochi Morio

  3rd Dept. Of Internal Med. Tokyo University School Of Medicine.

• Kuramochi Morio

  Third Department Of Internal Medicine Nagasaki University School Of Medicine

• Fjii Jun

  Inst. Adult Dis. Asahi Life Foundation.

• Kuramochi Morio

  The Institute For Adult Diseases Asahi Life Foundation

• SEKI Akira

  Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo

• Fujii Jun

  Institute For Adult Dis. Asalli Life Foudation

• Fujii Jun

  The Institute For Adult Diseases Asahi Life Foundation.

• Fujii Jun

  Institute For Adult Diseases Asahi Life Foundation Shinjuku

• KURAMOCHI Morio

  Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo

• KURAMOCHI Morio

  Third Department of Internal Medicine and Central iagnostic Laboratory, Nagasaki University School of Medicine

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