Prophylactic Efficacy of Desmopressin Acetate for Diabetes Insipidus after Hypophysectomy in the Dog
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概要
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The prophylactic efficacy of desmopressin acetate (DDAVP) on diabetes insipidus (DI) after hypophysectomy was investigated in the dog. In the control group, hypernatremia with a plasma level of 155 mEq/l or higher persisted for 12 hr from the 4th to the 16th hour after hypophysectomy, and symptoms of DI developed within five days after surgery. In the DDAVP treatment group, these changes were not observed, showing that administration of DDAVP (4 μg, instillation, twice daily) effectively prevented hypernatremia that develops immediately after surgery and DI-like symptoms that persists for about one week after surgery.
著者
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Nezu Yoshinori
Division Of Veterinary Surgery Department Of Veterinary Science Faculty Of Veterinary Medicine Nippo
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Hara Yasushi
Division Of Veterinary Surgery Nippon Veterinary And Animal Science University
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Tagawa Masahiro
Division Of Surgery Nippon Veterinary And Animal Science University
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Hasegawa Daisuke
Division Of Forest And Biomaterials Science Graduate School Of Agriculture Kyoto University
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MASUDA Hiroyuki
Division of Veterinary Surgery, Nippon Veterinary and Animal Science University
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MASUDA Hiroyuki
Division of Veterinary Surgery, Department of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University
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TAODA Takahiro
Division of Veterinary Surgery, Department of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University
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FUJITA Yukihiro
Division of Veterinary Surgery, Nippon Veterinary and Animal Science University
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TAODA Takahiro
Division of Veterinary Surgery, Nippon Veterinary and Animal Science University
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