Molecular and Phenotypic Characteristics of CMY-2 β-Lactamase-Producing Salmonella enterica Serovar Typhimurium Isolated from Cattle in Japan
スポンサーリンク
概要
- 論文の詳細を見る
Isolates of extended-spectrum cephalosporin (ESC)-resistant Salmonella enterica serovar Typhimurium obtained from two different farms in Fukushima Prefecture, Japan, in 2007, were characterized in order to determine the genetic basis of resistance. ESC resistance in the two isolates was mediated by an AmpC β-lactamase encoded by the blaCMY-2 gene, which is located in a large self-transmissible plasmid in each isolate. The sizes of the blaCMY-2-carrying plasmids were different. The replicon types of the plasmids were I1-Iγ and A/C. Results of macrorestriction analysis and phage typing suggest a close relationship between both isolates. This is the first report of ESC-resistant S. Typhimurium isolated from cattle in Japan.
著者
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AKIBA Masato
Safety Research Team, National Institute of Animal Health
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WATANABE Haruo
Department of Bacteriology, National Institute of Infectious Diseases
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Watanabe Haruo
Department Of Bacteriology I National Institute Of Infectious Diseases
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Izumiya Hidemasa
Department of Bacteriology I, National Institute of Infectious Diseases
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SUGAWARA Masaru
Aizu Livestock Hygiene Service Center
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KOMORI Junko
Iwaki Livestock Hygiene Service Center
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KAWAKAMI Marimo
Kenchu Livestock Hygiene Service Center
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