Bosentan Ameliorated Exercise-Induced Pulmonary Arterial Hypertension Complicated with Systemic Sclerosis
スポンサーリンク
概要
- 論文の詳細を見る
Pulmonary arterial hypertension (PAH) is a frequent complication in patients with systemic sclerosis. Bosentan is used in patients with symptomatic PAH; however, it has not been established whether or not bosentan ameliorates the progression of PAH in patients with no PAH-related symptoms. We present a case of systemic sclerosis with no PAH-related symptoms in which bosentan ameliorated exercise-induced PAH evaluated by 6-minute walk stress echocardiography, brachial flow-mediated dilation, and skin temperature of hands and feet. The results suggest that administration of bosentan in patients with early-stage PAH ameliorates pulmonary arterial vasodilatation through improvement of endothelial function.
- 社団法人 日本内科学会の論文
著者
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Yamada Hirotsugu
The University of Tokushima Graduate School of Medicine
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Soeki Takeshi
Department of Biochemistry, National Cardiovascular Center Research Institute
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Sata Masataka
Department Of Advanced Clinical Science And Therapeutics Graduate School Of Medicine University Of T
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Aihara Ken-ichi
Department Of Medicine And Bioregulatory Sciences The University Of Tokushima Graduate School Of Hea
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Yamada Hirotsugu
Department Of Cardiovascular Medicine Institute Of Health Bioscience Research The University Of Toku
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Niki Toshiyuki
Department Of Cardiovascular Medicine Institute Of Health Biosciences The University Of Tokushima Gr
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Tomita Noriko
Department Of Cardiovascular Medicine Institute Of Health Biosciences The University Of Tokushima Gr
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Wakatsuki Tetsuzo
Department Of Cardiovascular Medicine Institute Of Health Biosciences The University Of Tokushima Gr
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Koshiba Kunihiko
Department Of Cardiovascular Medicine Institute Of Health Biosciences The University Of Tokushima Gr
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Yagi Shusuke
Department Of Cardiovascular Medicine The University Of Tokushima Graduate School Of Health Bioscien
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Kusunose Kenya
Department Of Cardiovascular Medicine Institute Of Health Biosciences The University Of Tokushima Gr
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Iwase Takashi
Department Of Cardiovascular Medicine The University Of Tokushima Graduate School Of Health Bioscien
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Yamaguchi Koji
Department Of Anesthesiology Nagasaki University School Of Medicine
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Hirata Yoichiro
Department Of Cardiovascular Medicine Institute Of Health Biosciences The University Of Tokushima Gr
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Akaike Masashi
Department Of Cardiovascular Medicine Institute Of Health Biosciences The University Of Tokushima Gr
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Taketani Yoshio
Department Of Cardiology And Clinical Research National Hospital Organization Zentsuji Hospital
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Sumitomo-Ueda Yuka
Department of Medicine and Bioregulatory Sciences, The University of Tokushima Graduate School of Health Biosciences
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Dagvasumberel Munkhbaatar
Department of Cardiovascular Medicine, The University of Tokushima Graduate School of Health Biosciences
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Aihara Ken-ichi
Department of Medicine and Bioregulatory Sciences, The University of Tokushima Graduate School of Health Biosciences
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Kusunose Kenya
Department of Cardiovascular Medicine, The University of Tokushima Graduate School of Health Biosciences
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YOSHIDA SUMIKO
Department of Health and Welfare Science, Sendai College
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MATSUMOTO Toshio
Department of Medicine and Bioregulatory Science (the First Department of Internal Medicine), School of Medicine, The University of Tokushima
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Tomita Noriko
Department of Cardiovascular Medicine, The University of Tokushima Graduate School of Health Biosciences
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