Yogurt Containing Lactobacillus gasseri OLL 2716 (LG21 yogurt) Accelerated the Healing of Acetic Acid-Induced Gastric Ulcer in Rats
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概要
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We have reported that LG21 yogurt containing Lactobacillus gasseri OLL 2716 (LG21 yogurt) inhibits the formation of HCl-induced acute gastric lesions through the generation of prostaglandin E2. This study aimed to determine the role of viable Lactobacillus in the healing of acetic acid-induced chronic gastric ulcer. LG21 yogurt or γ-ray radiated LG21 yogurt was administered orally twice a day for 10 d at a dose of 5 ml/kg. LG21 yogurt significantly accelerated the healing of the ulcer, but γ-ray radiated LG21 yogurt did not. However, both yogurts significantly inhibited HCl-induced gastric erosive lesions and enhanced the generation of gastric mucosal prostaglandin E2. From the above results, it was found that viable bacteria are needed to accelerate the healing of chronic gastric ulcer, but not to inhibit gastric lesions.
- 社団法人 日本農芸化学会の論文
著者
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UCHIDA Masayuki
Food Science Institute, Division of Research and Development, Meiji Dairies Corporation
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Uchida Masayuki
Food Science Institute Division Of Research And Development Meiji Dairies Corporation
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Shimizu Kimiko
Food Sci. Inst. Div. Of Res. And Dev. Meiji Dairies Corp.
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KURAKAZU Keiko
Food Science Institute, Division of Research and Development, Meiji Dairies Corporation
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