Cloning of Prepro-Adrenomedullin and mRNA Expression in Cats
スポンサーリンク
概要
- 論文の詳細を見る
The objective of this paper was to evaluate sequence of feline prepro-adrenomedullin (AM) and its tissue distribution, and to investigate whether expression of feline AM mRNA increases in association with spontaneous cardiomyopathy. The feline prepro-AM cDNA sequence and deduced amino acids were 564 base pairs and 188 residues, respectively. The cDNA sequences of feline prepro-AM including AM and proadrenomedullin N-temainal 20 peptide showed high homology with those of other mammalian species. The mRNA expression of AM was detectable in the various normal tissues. The mRNA levels of AM were elevated in hearts with cardiomyopathy compared with normal. This study suggested that AM has important role as a neurohumoral factor in cats with spontaneous heart diseases.
- 社団法人 日本獣医学会の論文
著者
-
ASANO Kazushi
Laboratory of Veterinary Surgery, Department of Veterinary Clinical Sciences, Graduate School of Vet
-
KANNO Nobuyuki
Laboratory of Veterinary Surgery, Department of Veterinary Medicine, College of Bioresource Science,
-
TANAKA Shigeo
Laboratory of Veterinary Surgery, Department of Veterinary Medicine, College of Bioresource Science,
-
Asano Kazushi
Laboratory Of Veterinary Surgery Department Of Veterinary Clinical Sciences Graduate School Of Veter
-
EDAMURA Kazuya
Laboratory of Veterinary Emergency Medicine, Graduate School of Agricultural and Life Sciences, The
-
Edamura Kazuya
Laboratory Of Veterinary Emergency Medicine Graduate School Of Agricultural And Life Sciences The Un
-
TESHIMA Kenji
Laboratory of Veterinary Surgery, Department of Veterinary Medicine, College of Bioresource Sciences
-
SEKI Mamiko
Laboratory of Veterinary Surgery, Department of Veterinary Medicine, College of Bioresource Sciences
関連論文
- Evaluation of Plasma N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) Concentrations in Dogs with Mitral Valve Insufficiency
- POSイヌ骨肉腫細胞におけるビタミンDおよびレチノイドのアポトーシス誘導能(短報)
- En Block Resection of Large Hepatocellular Carcinoma Involving the Caudal Vena Cava in a Dog
- Assessment of Left Ventricular Function Using Pulsed Tissue Doppler Imaging in Healthy Dogs and Dogs with Spontaneous Mitral Regurgitation
- Evaluation of Left Ventricular Tei Index (Index of Myocardial Performance) in Healthy Dogs and Dogs with Mitral Regurgitation
- Biocompatibility of two different types of extracellular matrix in bioartificial endocrine pancreas in dogs: a preliminary report
- Comparative Study of Adult Porcine Pancreatic Endocrine Cell Preparation Using a Technique of Multiple Injections and Pancreatic Duct Cannulation Without a Proteolytic Enzyme
- Cloning of Prepro-Adrenomedullin and mRNA Expression in Cats
- Gene Expression of Adrenomedullin in Canine Normal Tissues and Diseased Hearts
- Hemodynamic and Biochemical Changes during Total Hepatic Vascular Exclusion in Dogs
- Seroprevalence of Bartonella henselae, Toxoplasma gondii, FIV and FeLV Infections in Domestic Cats in Japan
- Evaluation of Right Ventricular Tei Index (Index of Myocardial Performance) in Healthy Dogs and Dogs with Tricuspid Regurgitation
- Fibrodysplasia Ossificans Progressiva-like Condition in a Cat
- Clinicopathological studies on atrial and brain natriuretic peptide in canine heart disease
- Proliferation Capacity, Neuronal Differentiation Potency and Microstructures after the Differentiation of Canine Bone Marrow Stromal Cells into Neurons
- Comparison of Oral Robenacoxib and Carprofen for the Treatment of Osteoarthritis in Dogs: A Randomized Clinical Trial
- Perivertebral B-Cell Lymphoma in a Queensland Koala (Phascolarctos cinereus adustus) with Paralytic Symptoms in the Hind Limbs
- Plasma Adrenomedullin Concentration in Dogs with Myxomatous Mitral Valvular Disease
- Clinical Significance of Circulating Vascular Endothelial Growth Factor in Dogs with Mammary Gland Tumors
- Gene Expression of Growth Factors and Growth Factor Receptors for Potential Targeted Therapy of Canine Hepatocellular Carcinoma
- Effects of Cryopreservation on the Cell Viability, Proliferative Capacity and Neuronal Differentiation Potential of Canine Bone Marrow Stromal Cells