硬骨魚類のToll様受容体システム

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概要

• 論文の詳細を見る

• Toll-like receptors (TLRs) recognize the pathogen-associated molecular patterns (PAMPs) and play a pivotal role in modulating the immune response against invading pathogens. To date, many teleost TLRs have been identified by genome and transcriptome analysis. The orthologs involved in the TLR signalings have also been identified in teleosts. The comparison of the TLR functions in teleosts and mammals may provide significant information that will aid our understanding of host-pathogen interactions in teleosts. In this paper, we summarize of the literature regarding teleost TLRs, focusing on the similarities and differences between TLR mechanisms in teleosts and mammals. In addition, perspectives for future studies on teleost TLRs and the application of TLRs to aquaculture are discussed.

• 日本魚病学会の論文

著者

• KONDO Hidehiro

  Laboratory of Genome Science, Tokyo University of Marine Science and Technology

• AOKI Takashi

  Laboratory of Genome Science, Tokyo University of Marine Science and Technology

• HIRONO Ikuo

  Laboratory of Genome Science, Tokyo University of Marine Science and Technology

• 高野 倫一

  Aquatic Animal Health Division, National Research Institute of Aquaculture, Fisheries Research Agenc

• HWANG Seong

  Laboratory of Genome Science, Tokyo University of Marine Science and Technology

• 近藤 秀裕

  Laboratory of Genome Science, Tokyo University of Marine Science and Technology

• 高野 倫一

  Aquatic Animal Health Division National Research Institute Of Aquaculture Fisheries Research Agency

• Sano Motohiko

  Aquatic Animal Health Division, National Research Institute of Aquaculture, Fisheries Research Agenc

• Hwang Seong

  Laboratory Of Genome Science Tokyo University Of Marine Science And Technology

• Hirono Ikuo

  Laboratory Of Genetics And Biochemistry Department Of Aquatic Biosciences Tokyo University Of Fisher

• 近藤 秀裕

  Laboratory Of Genome Science Tokyo University Of Marine Science And Technology

• Kondo Hidehiro

  Laboratory Of Aquatic Molecular Biology And Biotechnology Graduate School Of Agricultural And Life S

• Takano Tomokazu

  Aquatic Animal Health Division, National Research Institute of Aquaculture, Fisheries Research Agenc

• Takano Tomokazu

  Aquatic Animal Health Div. National Res. Inst. Of Aquaculture Fisheries Res. Agency

• Aoki Takashi

  Laboratory Of Genome Science Tokyo University Of Marine Science And Technology

• 近藤 秀裕

  Laboratory Of Genome Science Graduate School Of Marine Science And Technology Tokyo University Of Ma

• Aoki Takashi

  Laboratory Of Genome Science Graduate School Of Marine Science And Technology Tokyo University Of Ma

• Aoki Takashi

  Laboratory For Applied Polymer Chemistry Department Of Polymer Science And Engineering Kyoto Institu

• Sano Motohiko

  Aquatic Animal Health Division, National Research Institute of Aquaculture, Fisheries Research Agency

• Takano Tomokazu

  Aquatic Animal Health Division, National Research Institute of Aquaculture, Fisheries Research Agency

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