Analysis of Three-Dimensional Characteristics in Tumor Morphology
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概要
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Precise assessment of therapeutic response in radiotherapy has been an important issue in the field of radiation oncology. This study proposed a methodology to evaluate therapeutic response based on tumor geometries. Three-dimensional (3D) tumor shapes were obtained from follow-up CT scans taken once a week throughout the treatment period. Tumor geometries were represented in two-dimensional (2D) surface geometry maps. These maps indicated the distances from the tumor center to surface at each azimuthal and horizontal angle by colors, in order to represent the characteristics of tumor morphologies. This method was applied to three clinical cases of head and neck cancer. The changes of tumor geometries could be represented visually and quantitatively using surface geometry maps. These maps provided valuable information about tumors for accurate diagnosis of tumor response to radiotherapy.
著者
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Tadano Shigeru
Division Of Human Mechanical Systems And Design Graduate School Of Engineering Hokkaido University
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Shirato Hiroki
Department Of Diagnostic And Interventional Radiology Hokkaido University Hospital
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Takao Seishin
Division Of Human Mechanical Systems And Design Graduate School Of Engineering Hokkaido University
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TAGUCHI Hiroshi
Department of Agricultural Chemistry, Faculty of Agriculture, Mie University
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