A Cross-sectional Survey of Chronic Kidney Disease and Diabetic Kidney Disease in Japanese Type 2 Diabetic Patients at Four Urban Diabetes Clinics
スポンサーリンク
概要
- 論文の詳細を見る
Objective Management of chronic kidney disease (CKD) is a critical issue in public health in attempt to prevent kidney failure and dialysis dependency. Since 1998, diabetes mellitus has been the leading cause of dialysis dependency in Japan. Previous reports demonstrated that the prevalence of CKD in diabetic patients was high; however albuminuria was not always present. This cross-sectional survey was performed 1) to indicate the prevalence of CKD and co-morbid illness in diabetic patients seen at diabetic clinics, and 2) to demonstrate the relationship between estimated glomerular filtration rate (eGFR) and urine albumin to creatinine ratio (ACR). Patients and Methods A total of 288 consecutive adult type 2 diabetic patients seen at four diabetic clinics in the Tokyo Metropolitan Area were enrolled in November 2007. We excluded patients with kidney failure. Estimated GFR was calculated by the MDRD Study equation with the Japanese coefficient. Results Patients had a mean age (+/- SD), 61 (+/- 12); male, 58%; mean BMI, 25.2 kg/m2 (+/- 5.2); and mean HbA1c, 7.1% (+/- 1.3). The prevalence of CKD stage 3 was 38% (109/288) with 64% (70/109) of them being normoalbuminuric. Co-morbid illnesses, including hypertension (p<0.001) and old stroke (p=0.02), were significantly higher in CKD stage 3 patients. Conclusion Our patients were relatively young and obese, reflecting urban clinical settings. The prevalence of CKD stage 3 patients was high. Clinicians need to check both eGFR and ACR to avoid underdiagnosis of CKD and diabetic kidney disease.
著者
-
Watanabe Yuko
Department of Internal Medicine, Tama-center Mirai Clinic
-
Fujii Hitomi
Department of Internal Medicine, Tama-center Mirai Clinic
-
Aoki Kanemi
Department of Internal Medicine, JA Isehara Kyodo Hospital
-
Kanazawa Yasuhiko
Department of Internal Medicine, JA Isehara Kyodo Hospital
-
Miyakawa Takaichi
Department of Internal Medicine, Tama-center Mirai Clinic
-
Watanabe Yuko
Department of Bacteriology and Pathology, Kanagawa Prefectural Public Health Laboratory
関連論文
- A Cross-sectional Survey of Chronic Kidney Disease and Diabetic Kidney Disease in Japanese Type 2 Diabetic Patients at Four Urban Diabetes Clinics
- Moraxella catarrhalis Does Not Grow on Nutrient Agar without Sodium Chloride Supplementation
- Refractory chronic immune thrombocytopenic purpura in a child with acute lymphoblastic leukemia
- Erythromycin Resistance Genes in Streptococcus pyogenes Isolates in Kanagawa, Japan
- Mental state and sensory thresholds
- Efficiency of Sodium Hypochlorite and Calcinated Calcium in Killing Escherichia coli O157 : H7, Salmonella spp., and Staphylococcus aureus Attached to Freshly Shredded Cabbage
- Primary gingival angiosarcoma successfully treated by radiotherapy with concurrent intra-arterial chemotherapy
- Vincristine-resistant Kasabach-Merritt phenomenon successfully treated with low-dose radiotherapy
- Clinical features of adult-onset chronic active Epstein-Barr virus infection : a retrospective analysis
- Statistical Parametric Mapping for Effects of Verapamil on Olfactory Connections of Rat Brain in Vivo using Manganese-enhanced MR Imaging
- Cautions and Strategy for Treating Chronic Heart Failure by Using Adaptive Servo-Ventilation
- Rapid Amelioration of Hyperglycemia Facilitated by Dasatinib in a Chronic Myeloid Leukemia Patient with type 2 Diabetes Mellitus
- Detection of Cryptosporidium sp. Oocyst and Giardia sp. Cyst in Faucet Water Samples from Cattle and Goat Farms in Taiwan
- ^F-FDG uptake in primary gastric malignant lymphoma correlates with glucose transporter 1 expression and histologic malignant potential