A Familial Case of Autoimmune Hepatitis
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概要
- 論文の詳細を見る
Autoimmune hepatitis is a chronic liver disease, and both genetic background and environmental factors are related to its pathogenesis. Here, we report that out of five members of a family with similar human leukocyte antigen haplotypes, two developed autoimmune hepatitis, one was positive for antinuclear antibody, and the remaining two had no features of autoimmunity. The two patients with autoimmune hepatitis had a history of medication use, whereas the other family members did not. Our familial study suggests that in addition to genetic background, medication use and other environmental factors may be related to the onset of autoimmune hepatitis.
- 社団法人 日本内科学会の論文
著者
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Murata Yosuke
Department Of Biology New Drug Research Laboratories Kanebo Ltd.
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Matsuura Bunzo
Department Of Gastroenterology And Metabology Ehime University Graduate School Of Medicine
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Hamada Maho
Department Of Gastroenterology And Metabology Ehime University Graduate School Of Medicine
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Akbar Fazle
Department Of Gastroenterology And Metabology Ehime University Graduate School Of Medicine
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Onji Morikazu
Department Of Gastroenrerology And Metabology Ehime University Graduate School Of Medicine
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Abe Masanori
Department Of Anesthesiology Faculty Of Medicine University Of The Ryukyus
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Furukawa Shinya
Department Of Applied Chemistry Faculty Of Engineering
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Yoshida Osamu
Department Of Agricultural Chemistry Faculty Of Horticulture Chiba University
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Michitaka Kojiro
Department of Endoscopic Medicine, Ehime University Graduate School of Medicine
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Hiasa Yoichi
Department of Gastroenterology and Metabiology, Ehime University Graduate School of Medicine, Japan
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Matsuura Bunzo
Department of Gastroenterology and Metabiology, Ehime University Graduate School of Medicine, Japan
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