Eosinophil-Associated Gastrointestinal Disorders with Asthma: Immunohistochemical Analyses
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概要
- 論文の詳細を見る
We report 5 patients with eosinophil-associated gastrointestinal disorders (EGIDs) and asthma. All patients developed EGIDs while asthma remained clinically stable. Asthma severity was moderate persistent and severe persistent and 2 patients had intolerance to nonsteroidal anti-inflammatory drugs. By immunohistochemical analysis of the mucosa, eosinophils, macrophages, and T cells were found to be the major infiltrating cells. There was a lesser degree of infiltration of mast cells and B cells but no neutrophils. Compared with normal controls, increased counts of eosinophils and CD8+ T cells were found in the duodenum, and eosinophils, macrophages, and CD4+ T cells in the colon.
著者
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Chida Kingo
Department Of Pathology Iwata City Hospital
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Komiyama Akira
Department Of Lightwave Sciences Osaka Electro-communication University
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Shirai Toshihiro
Department Of Internal Medicine Fujinomiya City General Hospital
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Hayakawa Hiroshi
Departmennt Of Pediatrics Mejirodai Campus University Of Tokyo
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Suda Takafumi
Department Of Respiratory Medicine Hamamatsu University School Of Medicine
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CHIDA Kingo
Department of Respiratory Medicine, Hamamatsu University School of Medicine
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Hashimoto Dai
Department of Respiratory Medicine, Hamamatsu University School of Medicine
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