Anaphylaxis to Aprotinin in Fibrin Sealant
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概要
- 論文の詳細を見る
A 50-year-old man with chronic otitis media was admitted to our hospital for investigation of lung cancer. He had received repeated instillations of fibrin sealant (Bolheal) in myringoplasty 7 times over 12 months. During the lower lobectomy, soon after fibrin sealant was applied to seal bronchopleural fistulas, systolic blood pressure decreased to 60 mmHg. Treatment with epinephrine and dopamine was required until his condition improved 2 days later. The specific IgE antibody was detected for the solution for fibrinogen and factor XIII containing bovine aprotinin. Cross-reactivity between purified aprotinin and the solution was noted by competitive ELISA inhibition tests.
- 社団法人 日本内科学会の論文
著者
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Chida Kingo
Second Department Of Internal Medicine Hamamatsu University School Of Medicine
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Yasueda Hiroshi
Clinical Research Center For Allergy And Rheumatology National Hospital Organization Sagamihara Nati
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Shirai Toshihiro
Department Of Internal Medicine Fujinomiya City General Hospital
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SANO Shinichi
Kyoai Clinic, Fujinomiya
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SHIRAI Toshihiro
Departments of Internal Medicine and Surgery, Fujinomiya City General Hospital
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YASUEDA Hiroshi
Clinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital
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SHIMOTA Hiroshi
Departments of Internal Medicine and Surgery, Fujinomiya City General Hospital
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TAKEUCHI Yasuo
Clinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital
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