Relationship between Radiation Pneumonitis and Prognosis in Patients with Primary Lung Cancer Treated by Radiotherapy
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概要
- 論文の詳細を見る
Relationship between the grade of radiation pneumonitis (RP) and treatment outcome in lung cancer patients has not been clarified yet. The purpose of this study was to retrospectively evaluate the relationship in patients with primary lung cancer treated by radiotherapy. One hundred thirty-five patients who underwent definitive radiotherapy with known grade of RP were analyzed. RP was scored by using the Radiation Therapy Oncology Group (RTOG) acute radiation morbidity scoring criteria. Survival and local control data were analyzed in relation to the grade of RP. RP was grade 0 in 5 patients, grade 1 in 71, grade 2 in 39, grade 3 in 15 (11%), grade 4 in 0 and grade 5 in 5 (3.7%). There were no significant correlations between patient or tumor characteristics and grade of RP. Excluding 5 patients with grade 5 pneumonitis, survival rates were similar between those with grade 0 or 1 pneumonitis and those with grade 2 or 3. Also, there was no difference in survival between patients with grade 0-2 pneumonitis and those with grade 3. Local control rates were similar between the two groups. Grade of RP did not appear to be associated with prognosis when patients with grade 5 pneumonitis were excluded from analysis.
- 久留米大学医学部 The Kurume Medical Journal 編集部の論文
著者
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HORII Naotoshi
Department of Radiology, Kishiwada City Hospital
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Ogino Hiroyuki
Department Of Radiology Nagoya City University Graduate School Of Medical Sciences
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Horii Naotoshi
Department Of Radiology Kishiwada City Hospital
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Shibamoto Yuta
Department Of Oncology Chest Disease Research Institute Kyoto University
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YAMANO MOTOTSUGU
Department of Radiology, Nagoya City University Graduate School of Medical Sciences
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