Rapidly Progressed Secondary Amyloidosis in a Patient with Mixed Connective Tissue Disease
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概要
- 論文の詳細を見る
A 39-year-old woman with mixed connective tissue disease suddenly developed repeated watery diarrhea two years after the onset of the disease. A colonic biopsy specimen revealed amyloid A protein deposition and the diagnosis of secondary amyloidosis was established. The amyloid deposition disappeared after the 8-month course of the treatment with prednisolone and azathioprine. Molecular genetic analysis showed the presence of the γ-allele in her serum amyloid A protein 1 gene. This might be associated with the early onset and progression of secondary amyloidosis in our case, just like cases reported in rheumatoid arthritis.
- 社団法人 日本内科学会の論文
- 2004-09-01
著者
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KOMATSUDA Atsushi
Third Department of Internal Medicine, Akita University School of Medicine
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SAWADA Ken-ichi
Third Department of Internal Medicine, Akita University School of Medicine
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BABA SATOSHI
Second Department of Pathology, Hamamatsu University School of Medicine
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Kimura Hirotaka
Department of Cardiology, The Heart Institute of Japan, Tokyo Women's Medical University
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Baba Satoshi
Second Department Of Pathology Hamamatsu University School Of Medicine
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MINOTA Seiji
Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical School
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MIMORI Akio
Division of Rheumatology, International Medical Center of Japan
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Mimori Akio
Division Of Rheumatic Diseases International Medical Center Of Japan
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Mimori Akio
Division Of Rheumatology International Medical Center Of Japan
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Sawada Ken-ichi
Third Department Of Internal Medicine Akita University School Of Medicine
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Kimura Hirotaka
Department Of Cardiology Tokyo Women's Medical College
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Kimura Hirotaka
Department Of Internal Medicine Ugo Municipal Hospital
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Komatsuda Atsushi
Third Department Of Internal Medicine Akita University School Of Medicine
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Minota Seiji
Division Of Rheumatology And Clinical Immunology Department Of Internal Medicine Jichi Medical Schoo
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