Heart Failure with Silent Coronary Artery Spasm Exhibiting Microscopic Focal Myocardial Necrosis and Amyloid-Deposition
スポンサーリンク
概要
- 論文の詳細を見る
We report a 67-year-old Japanese man who presented with worsening heart failure with asymptomatically transient ischemic ST-segment depression. Left ventriculography showed diffuse hypokinesis; asymptomatic coronary artery spasm was evoked by the acetylcholine provocation test. Endomyocardial biopsy exhibited hypertrophic cardiomyocytes and scattered microscopic focal myocardial necrosis with amyloid-deposition. Transient ST-segment depression improved after treatment with a calcium antagonist, but cardiac contraction was still impaired. We hypothesize that asymptomatic coronary spasm may cause irreversible cardiac damage and heart failure with amyloid-deposition; the presence or absence of coronary spasm in heart failure patients should be clarified in order to determine therapeutic strategy.
- 社団法人 日本内科学会の論文
- 2004-03-01
著者
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Hirai Nobutaka
Kumamoto AMI Study Group
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Sakashita Naomi
Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University
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Yoshimura Michihiro
The Division of Cardiology, Department of Internal Medicine, Jikei University School of Medicine
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Suzuki Satoru
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
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Suzuki Satoru
The Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
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Sugiyama Seigo
The Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
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Ogawa Hisao
The Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
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SAKAMOTO TOMOHIRO
The Division of Cardiology, Kumamoto University School of Medicine
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USUKU Hiroki
the Department of Cardiovascular Medicine, Graduate School of Medical Sciences Kumamoto University
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HIRAI Nobutaka
the Department of Cardiovascular Medicine, Graduate School of Medical Sciences Kumamoto University
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KAIKITA Koichi
the Department of Cell Pathology, Graduate School of Medical Sciences Kumamoto University
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SAKASHITA Naomi
the Department of Cardiovascular Medicine, Graduate School of Medical Sciences Kumamoto University
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Satoh Toru
Division Of Cardiology Saiseikai Kumamoto Hospital Cardiovascular Center
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Usuku Hiroki
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
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Sakashita Naomi
Department Of Cell Pathology Graduate School Of Medical Sciences Kumamoto University
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Yoshimura Michihiro
The Division Of Cardiology Department Of Internal Medicine Jikei University School Of Medicine
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Yoshimura Michihiro
The Department of Cardiology, The Jikei University School of Medicine
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