Autologous Stem Cell Transplantation using MEAM Regimen for Relapsed AIDS-Related Lymphoma Patients Who Received Highly Active Anti-Retroviral Therapy: A Report of Three Cases
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概要
- 論文の詳細を見る
AIDS-related lymphoma (ARL) is a serious complication of HIV infection. We performed MEAM (MCNU + etoposide + cytarabine + L-PAM) regimen with autologous stem cell transplantation (ASCT) for three patients with refractory or relapsed ARL. All three patients had been treated with highly active anti-retroviral therapy (HAART) during the course of the treatment regimen and ASCT. The regimen was well tolerable, and no uncontrollable infection was noted. All patients are still alive and maintain complete remission at 24, 20 and 9 months after transplantation. ASCT using MEAM regimen as a conditioning regimen was feasible for our patients with refractory or relapsed ARL.
著者
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Oka Shinichi
Aids Clinical Center International Medical Center Of Japan
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Tachikawa Natsuo
AIDS Clinical Center, International Medical Center of Japan
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MIWA Akiyoshi
Division of Hematology, Department of Medicine, Hospital, International Medical Center of Japan
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Hagiwara Shotaro
Division Of Hematology Department Of Internal Medicine National Center For Global Health And Medicine
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KAWABATA Kimihito
Division of Cellular Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo
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Takenouchi Ayako
Division of Hematology, Internal Medicine, International Medical Center of JAPAN
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Miwa Akiyoshi
Division of Hematology, Internal Medicine, International Medical Center of JAPAN
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Tanuma Junko
AIDS Clinical Center, International Medical Center of JAPAN
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Tanimura Akira
Division of Hematology, Internal Medicine, International Medical Center of JAPAN
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