Type 1 Diabetes Mellitus Provoked by Peginterferon .ALPHA.-2b Plus Ribavirin Treatment for Chronic Hepatitis C
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概要
- 論文の詳細を見る
A 51-year-old man developed type 1 diabetes mellitus following 24 weeks of treatment with recombinant α-2b peginterferon plus ribavirin for chronic hepatitis C. Pancreatic autoantibody tests were negative before the start of therapy, but a significant increase in glutamic acid decarboxylase (GAD) antibody titer was seen after 24 weeks of treatment. Six months after the onset of type 1 diabetes mellitus, the patient continues to receive 40 units of insulin daily. The clinical course suggested that recombinant α-2b peginterferon plus ribavirin provoked type 1 diabetes mellitus, therefore, in patients who are candidates for interferon therapy the presence of pancreatic autoantibodies and the fasting plasma glucose level should be investigated before and during treatment.
- 社団法人 日本内科学会の論文
著者
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Fuke Hiroyuki
Department Of Internal Medicine Saiseikai Matsusaka General Hospital
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Takei Yoshiyuki
Department Of Gastroenterology And Hepatology Division Of Clinical Medicine And Biomedical Science I
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Ito Keiichi
Department Of Mathematics College Of Liberal Arts Kyoto University
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Yamamoto Norihiko
Department Of Surgery Moriguchi Keijinkai Hospital
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Shiraki Katsuya
Department of Gastoenterology, Mie University School of Medicine, Japan
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Tanaka Junichirou
Department of Gastroenterology, Mie University School of Medicine
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Sugimoto Kazushi
Department of Gastroenterology, Mie University School of Medicine
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Beppu Tetsuya
Department of Gastroenterology, Mie University School of Medicine
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Yoneda Kentarou
Department of Gastroenterology, Mie University School of Medicine
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Sugimoto Kazushi
Department of Gastoenterology, Mie University School of Medicine, Japan
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Beppu Tetsuya
Department of Gastroenterology, Mie University School Medicine
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Takei Yoshiyuki
Department of Gastoenterology, Mie University School of Medicine, Japan
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Yamamoto Norihiko
Department of Gastoenterology, Mie University School of Medicine, Japan
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Yamamoto Norihiko
Department of Gastroenterology, Mie University School of Medicine
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