Pulmonary Paragonimiasis with Coincidental Malignant Mesothelioma
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概要
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A 72-year-old man patient was referred to our institution for evaluation and treatment of right pleural effusion. Eosinophilic pleural effusion and peripheral eosinophilia were identified during the course of hospitalization. Pulmonary paragonimiasis was confirmed by the presence of paragonimus-specific IgG antibodies for Paragonimus (P.) westermani and P. miyazakii in his serum. Although Praziquantel, a highly effective agent for the treatment of lung flukes was repeatedly administered, the pleural effusion did not subside and the patients condition gradually deteriorated until his death due to circulatory insufficiency. Postmortem examination revealed malignant mesothelioma of the sarcomatous type encasing the right lung and heart. Cardiac involvement accompanied with old and recent-onset myocardial ischemic changes resulted in death of this patient. Here, we report a very rare case of malignant mesothelioma with a concomitant infection of parasitic lung fluke.
著者
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Uekusa Toshimasa
Department Of Laboratory Medicine Kanto Rousai Hospital
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IWASE Akihiko
Department of Infectious and Respiratory Medicine, Showa General Hospital
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Suzuki Masaru
Department Of Applied Physics And Chemistry The University Of Electro-communications
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Miyaji Atsuko
Department Of Respiratory Medicine Juntendo Tokyo Koto Geriatric Medical Center
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Fujii Hiroaki
Departmant Of Pathology Johns Hopkins University
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Nara Takeshi
Department Of Molecular And Cellular Parasitology Department Of Epidemiology And Environmental Healt
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Ohwada Akihiko
Department Of Respiratory Medicine Juntendo Tokyo Koto Geriatric Medical Center
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Yamazaki Hiroshi
Department Of Applied Chemistry Faculty Of Science And Engineering Chuo University
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Takahashi Kazuhisa
Department Of Applied Chemistry Faculty Of Science Science University Of Tokyo
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HIRAI Syu
Department of Pathology (I), Juntendo University School of Medicine
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OHWADA Akihiko
Department of Respiratory Medicine, Juntendo Tokyo Koto Geriatric Medical Center
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Suzuki Masaru
Department of Radiology, Juntendo Tokyo Koto Geriatric Medical Center
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Yamazaki Mariko
Department of Respiratory Medicine, Juntendo Tokyo Koto Geriatric Medical Center
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