SPONTANEOUS TUMORS IN F-344/Jcl RATS
スポンサーリンク
概要
- 論文の詳細を見る
The age-related incidence of spontaneously occuring neoplastic and non-neoplastic lesions in untreated F-344/Jcl rats, used as controls in carcinogenicity testing, were studied from the histological examination of tissues from 469 males and 354 females. The incidence of spontaneous tumors was 83.2% in the males and 71.2% in the females. The most common neoplasms were leukemia (males : 24.3%, females : 24.0%), pituitary adenoma (males : 16.0%, females : 45.2%), pheochromocytoma (males : 14.7% females : 7.3%, testicular interstitial cell tumor (males : 79.1%), and uterine endometrial stromal polyp(females : 16.4%). The incidence of other tumors of almost all the organs and/or tissues was low. Non-neoplastic lesions generally increased with advancing age of the animals.
- 日本トキシコロジー学会の論文
- 1989-08-25
著者
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Uekusa Toshimasa
Department Of Pathology (i) Juntendo University School Of Medicine
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Uekusa Toshimasa
Department Of Laboratory Medicine Kanto Rousai Hospital
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Aze Y
Ono Pharmaceutical Co. Ltd. Fukui Jpn
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Fukuda Yoshiro
Department Of Pathology School Of Medicine Juntendo University
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Fukuda Yoshiro
Department Of Pathology (i) Juntendo University School Of Medicine
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WAKABAYASHI Kazuo
Department of Public Health, National Defense Medical College
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TAKAKI Yuki
Department of Pathology (I), Juntendo University School of Medicine
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KITAMURA Sigehiro
Department of Pathology (I), Juntendo University School of Medicine
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HONMA Sakae
Department of Pathology (I), Juntendo University School of Medicine
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AZE Yoshiya
Department of Pathology (I), Juntendo University School of Medicine
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KUWABARA Noriyuki
Department of Pathology (I), Juntendo University School of Medicine
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Aze Yoshiya
Department Of Pathology (i) Juntendo University School Of Medicine
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Takaki Yuki
Department Of Pathology (i) Juntendo University School Of Medicine
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Honma Sakae
Department Of Pathology (i) Juntendo University School Of Medicine
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Kuwabara Noriyuki
Department Of Pathology (i) Juntendo University School Of Medicine
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Wakabayashi Kazuo
Department Of Public Health National Defense Medical College
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Wakabayashi K
National Defense Medical Coll. Tokorozawa
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Kitamura Sigehiro
Department Of Pathology (i) Juntendo University School Of Medicine
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Takaki Yuki
Department Of Metabolic Medicine Faculty Of Life Sciences Kumamoto University
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WAKABAYASHI Kazuo
Department of Pathology (I), Juntendo University School of Medicine
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