IgG4-related Autoimmune Prostatitis: Two Cases with or without Autoimmune Pancreatitis
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概要
- 論文の詳細を見る
Recently, autoimmune pancreatitis (AIP) has been reported with a variety of extra-pancreatic manifestations and infiltration of IgG4-positive cells into the affected organs. We report herein two cases with prostatitis. One was seen in a patient with typical AIP, and the other was observed without any clinical manifestation of AIP. Serum IgG4 levels were elevated in both cases. Histological examination of the prostates showed that parenchymal cells were partially or totally replaced with fibrosis and abundant infiltration of IgG4-positive cells. Significant uptake of [18F] fluorodeoxyglucose by the prostate was seen in both cases. In the case with AIP, the uptake completely disappeared after steroid therapy. The findings observed in these cases suggest that the pathological mechanism for prostatitis is similar to the mechanism previously implicated in AIP, namely IgG4-related autoimmune prostatitis.
著者
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Hiroi Makoto
Laboratory Of Diagnostic Pathology Kochi Medical School Hospital
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KOHSAKI Takuhiro
Department of Gastroenterology and Hepatology, Kochi Medical School
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Nishimori Isao
Department Of Gastroenterology And Hepatology Kochi Medical School
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Shuin Taro
Department Of Urology And Pathology I Kochi Medical School
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Kawa Shigeyuki
Center For Health Safety And Environmental Management Shinshu University
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Onishi Saburo
Department Of Gastroenterology And Hepatology Kochi Medical School
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Kohsaki Shino
Department Of Radiology Kochi Medical School
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Hamano Hideaki
Department Of Gastroenterology Shinshu University School Of Medicine
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Ogawa Yasuhiro
Deparment Of Cardiology Nagoya University Graduate School Of Medicine
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Kohsaki Takuhiro
Department Of Gastroenterology And Hepatology Kochi Medical School
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Matsumoto Manabu
Laboratory Of Diagnostic Pathology Kochi Medical School Hospital
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Hamano Hideaki
Department of Medicine, Gastroenterology, Shinshu University School of Medicine
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Matsumoto Manabu
Laboratory of Diagnostic Pathology, Kochi Medical School
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Kohsaki Shino
Department of Diagnostic Radiology and Radiation Oncology, Kochi Medical School
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