Acute-onset Sarcoidosis with Erythema Nodosum and Polyarthralgia (Loefgren's Syndrome) in Japan: a Case Report and a Review of the Literature
スポンサーリンク
概要
- 論文の詳細を見る
Löfgren's syndrome is an acute form of sarcoidosis that is characterized by erythema nodosum (EN), bilateral hilar lymphadenopathy (BHL), and polyarthralgia or polyarthritis. This syndrome is common among white people, but is considered rare among Japanese people. We present the case of a 26-year-old Japanese woman with Löfgren's syndrome. The patient complained of polyarthritis and EN of the lower extremities that lasted for 3 months. A chest radiograph revealed BHL and nodular shadows. The angiotensin-converting enzyme (ACE) level was within the normal range. Transbronchial lung biopsy revealed a noncaseating granuloma with giant cells. Six Japanese cases of Löfgren's syndrome have been reported previously. Five of the seven Japanese patients with Löfgren's syndrome had normal ACE levels; all of them exhibited BHL. Löfgren's syndrome should be considered as a possibility when examining a patient with EN and articular symptoms, even if the patient is Japanese.
- 社団法人 日本内科学会の論文
著者
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Kimura Yuichiro
Department of Cardiology, Odawara Municipal Hospital
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Nukiwa Toshihiro
Department Of Respiratory Medicine Division Of Cancer Control Institute Of Development Aging And Can
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Ohta Hiromitsu
Department Of Mechanical Engineering National Fishery University
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Ebina Masahito
Department Of Respiratory Medicine Tohoku University Graduate School Of Medicine
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MAEMONDO Makoto
Department of Respiratory Oncology and Molecular Medicine, Institute of Development, Aging and Cance
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Kikuchi Toshiaki
Deparment Of Applied Physics The National Defense Academy
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Nakamura Atsushi
Department Of Applied Physics Faculty Of Science Fukuoka University
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Ebina Masahito
Department of Respiratory Oncology and Molecular Medicine, Institute of Development, Aging, and Cancer, Tohoku University
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Tazawa Ryushi
Department of Respiratory Oncology and Molecular Medicine, Institute of Development, Aging, and Cancer, Tohoku University
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Kikuchi Toshiaki
Department of Respiratory Oncology and Molecular Medicine, Institute of Development, Aging, and Cancer, Tohoku University
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Maemondo Makoto
Department of Respiratory Oncology and Molecular Medicine, Institute of Development, Aging, and Cancer, Tohoku University
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