Polyarteritis Nodosa in Association with Subarachnoid Hemorrhage
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概要
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We report a 65-year-old man with classic polyarteritis nodosa (PAN) who developed subarachnoid hemorrhage. Polyarteritis nodosa was strongly suspected, however, the biopsy specimens of kidney and sural nerve showed no findings of vasculitis and the serum titer of antimyeloperoxidase-antineutrophil cytoplasmic autoantibody (MPO-ANCA) was negative. Cranial magnetic resonance angiography showed no findings of aneurysms. He developed subarachnoid hemorrhage (SAH) during the course and died. Autopsy confirmed fibrinoid necrosis in the medium-sized artery of multiple organs. To our knowledge, this is the first report of a case of classic PAN accompanied by SAH in which MPO-ANCA proved negative.
- 社団法人 日本内科学会の論文
著者
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Naritomi Hiroaki
Cerebrovascular Division Department Of Medicine National Cardiovascular Center
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Terai Tadashi
Department Of Medicine Shizuoka Shimizu Municipal Hospital
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Yamawaki Takemori
Department Of Clinical Neuroscience And Therapeutics Hiroshima University Graduate School Of Biomedical Sciences
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SHIGENO KOJI
Department of Internal Medicine, School of Medicine, Keio University
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Yamawaki Takemori
Department of Neurology, Nagoya City University
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Oomura Masahiro
Cerebrovascular Division, Department of Medicine, National Cardiovascular Center
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