Acute Eosinophilic Pneumonia Caused by CalciumStearate, an Additive Agent for an Oral Antihistaminic Medication
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概要
- 論文の詳細を見る
A 70-year-old man was admitted to our hospital because of dyspnea after taking an antihistaminic agent (homochlorcyclizine hydrochloride) for itching. Chest roentgenogram showed infiltration in the left lung field, and laboratory data revealed eosinophilia. Examination of the bronchoalveolar lavage fluid revealed an increased eosinophil count. A drug lymphocyte stimulation test was positive only for calcium stearate, an additive contained in the homochlorcyclizine hydrochloride tablet. The pulmonary infiltration and clinical symptoms subsided after withdrawal of all drugs and initiation of glucocorticoid therapy. Therefore, we concluded that this patient's pulmonary disease was caused by calcium stearate, an additive for an antihistaminic drug. An allergic reaction to a drug's additive material should be considered as a rare cause of drug-induced acute eosinophilic pneumonia.
- 社団法人 日本内科学会の論文
著者
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Touge Hirokazu
Division Of Medical Oncology And Molecular Respirology Faculty Of Medicine Tottori University
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Chikumi Hiroki
Division Of Medical Oncology And Molecular Respirology Faculty Of Medicine Tottori University
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Miyata Masanori
Division Of Medical Oncology And Molecular Respirology Faculty Of Medicine Tottori University
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Makino Haruhiko
Division Of Breast Oncology Niigata City General Hospital
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Kodani Masahiro
Division Of Medical Oncology And Molecular Respirology Faculty Of Medicine Tottori University
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Shimizu Eiji
Division Of Medical Oncology And Molecular Respirology Department Of Multidisciplinary Internal Medi
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Chikumi Hiroki
Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
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Kurai Jun
Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
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Sako Takanori
Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
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Watanabe Masanari
Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
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Hitsuda Yutaka
Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
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Makino Haruhiko
Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University
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