Effects of Excessive Ethanol Consumption on the Diagnosis of the Metabolic Syndrome Using Its Clinical Diagnostic Criteria
スポンサーリンク
概要
- 論文の詳細を見る
Objects Various morbid conditions constituting the metabolic syndrome could be also caused by excessive ethanol consumption. Thus, it is conceivable that excessive ethanol consumption may affect the diagnosis of the metabolic syndrome using its current diagnostic criteria. Here, we investigated this. Materials and Methods A cross-sectional study involving 2,130 Japanese man subjects aged 20 to 65 was performed. Results The rate of subjects judged to have metabolic syndrome using its diagnostic criteria for Japanese was 15.7%. However, the prevalence was significantly higher in excessive drinkers who consume more than 20 grams of ethanol per day (n=473, 22.0%) than average drinkers (n=1,657, 13.9%, χ2=18.0, p<0.0001). The rate of subjects who satisfied each component of the criteria of the metabolic syndrome, namely that of an excessive waist circumference, hypertension, dislipidemia, or hyperglycemia was significantly higher in the former than in the latter, respectively. When subjects with a waist circumferences of 85 cm or more were selectively studied, the prevalence of the metabolic syndrome was still higher in excessive drinkers (39.2%) than in average drinkers (32.4%, χ2=4.0, p=0.049), whereas the waist circumference was not significantly different between the two groups. Conclusion Excessive ethanol consumption is associated with an increased prevalence of the metabolic syndrome following the current clinical diagnostic criteria. Excessive ethanol consumption could simply be a factor worsening the metabolic syndrome. However, we must be aware of another possibility that excessive ethanol consumption increases the number of subjects regarded as the metabolic syndrome via mechanisms differing from visceral fat accumulation.
- 社団法人 日本内科学会の論文
著者
-
Saito Ikuo
Health Center Keio University
-
Hibi Toshifumi
Department Of Digestive Organ Medicine Keio University School Of Medicine
-
Ohgo Hideki
Department Of Gastroenterology School Of Medicine Keio University
-
Yokoyama Hirokazu
Health Center Keio University
-
Hiroshi Hirose
Health Center, School of Medicine, Keio University
-
Hiroshi Hirose
Health Center, Keio University
関連論文
- アンケート調査による生活習慣病家族歴の妥当性の検討
- DNMT1 and DNMT3b silencing sensitizes human hepatoma cells to TRAIL-mediated apoptosis via up-regulation of TRAIL-R2/DR5 and caspase-8
- Primary hepatic presentation of Hodgkin's lymphoma : A case report
- A case of primary hepatic non-Hodgkin's lymphoma with chronic hepatitis C
- Induction therapy with twice-daily interferon-beta does not improve the therapeutic efficacy of consensus interferon monotherapy for chronic hepatitis C
- Clinical impact of a newly developed capsule endoscope : usefulness of a real-time image viewer for gastric transit abnormality
- Treatment of hepatitis C virus with peg-interferon and ribavirin combination therapy significantly affects lipid metabolism
- Pouchitis atlas for objective endoscopic diagnosis
- Reliability, validity, and responsiveness of the Japanese version of the Inflammatory Bowel Disease Questionnaire
- Green Coffee Bean Extract and Its Metabolites Have a Hypotensive Effect in Spontaneously Hypertensive Rats
- NOVEL TECHNIQUE OF ENDOSCOPIC SUBMUCOSAL DISSECTION USING AN EXTERNAL GRASPING FORCEPS FOR SUPERFICIAL GASTRIC NEOPLASIA
- High throughput multiple combination extraction from large scale polymorphism data by exact tree method
- New mechanism of transforming growth factor-β signaling in hepatoma : Dramatic up-regulation of tumor initiating cells and epidermal growth factor receptor expression
- Induction of hepatic stellate cell proliferation by LPS-stimulated peripheral blood mononuclear cells from patients with liver cirrhosis
- In Half of Hypertensive Diabetics, Co-Administration of a Calcium Channel Blocker and an Angiotensin-Converting Enzyme Inhibitor Achieved a Target Blood Pressure of
- Cyclosporine for inflammatory bowel disease-an epoch-making therapy for corticosteroid-resistant or dependent patients?
- Reactivation of hepatitis B in a patient with Crohn's disease treated using infliximab
- Role of microRNAs on anti-cancer effect of a selective COX-2 inhibitor in human gastric cancer cells
- Therapeutic benefit of sulfasalazine for patients with primary sclerosing cholangitis
- Introduction and overview : recent advances in the immunotherapy of inflammatory bowel disease
- Laparoscopically assisted ileocecal resection for Crohn's disease associated with intestinal stenosis and ileovesical fistula
- Possible association of tumor necrosis factor receptor 2 gene polymorphism with severe hypertension using the extreme discordant phenotype design
- Characteristics of Reference Intervals of Metabolic Factors in Healthy Japanese : A Proposal to Set Generation- and Gender-Specific Diagnostic Criteria for Metabolic Syndrome
- Relations between Serum Reactive Oxygen Metabolites (ROMs) and Various Inflammatory and Metabolic Parameters in a Japanese Population
- Prevalence of Metabolic Syndrome in Young Men in Japan
- An Inverse Association between Serum Gamma Glutamyl Transpeptidase Activity and Breslow's Lifestyle Index; Its Practical Application for Screening of Subjects with Unhealthy Lifestyles
- Associations among Lifestyle Status, Serum Adiponectin Level and Insulin Resistance
- Relation between Blood Pressure and Rhinitis in a Japanese Adolescent Population
- Insulin Resistance and Hypertension : Seven-Year Follow-Up Study in Middle-Aged Japanese Men (the KEIO Study)
- Relation between Blood Pressure Control, Body Mass Index, and Intensity of Medical Treatment
- Effects of Body Weight Control on Changes in Blood Pressure : Three-Year Follow-Up Study in Young Japanese Individuals
- Sexual Differences in Relationships between Birth Weight or Current Body Weight and Blood Pressure or Cholesterol in Young Japanese Students
- Supplement. Obesity, Hypertension, Insulin Resistance and Lipid Disorders : Cross-sectopnal and Longitudinal Studies in Japanese Adolescents and Middle-aged Men
- Insulin Resistance Syndrome in Adolescents and Adults
- Esophageal melanosis, an endoscopic finding associated with squamous cell neoplasms of the upper aerodigestive tract, and inactive aldehyde dehydrogenase-2 in alcoholic Japanese men
- Development of consensus statements for the diagnosis and management of intestinal Behcet's disease using a modified Delphi approach
- Association of the -173G/C polymorphism of the macrophage migration inhibitory factor gene with ulcerative colitis
- Melanosis and squamous cell neoplasms of the upper aerodigestive tract in Japanese alcoholic men
- Sinusoidal endothelial fenestrae organization regulated by myosin light chain kinase and Rho-kinase in cultured rat sinusoidal endothelial cells
- Overview : Helicobacter pylori and Extragastric Disease
- Psychological aspects of inflammatory bowel disease
- Association of pseudomembranous colitis with Henoch-Schonlein purpura
- Circulating autoantibodies against purified colonic mucin in ulcerative colitis
- Immunosuppressive agents in the treatment of Crohn's disease and ulcerative colitis
- PJ-319 Efficacy and Safety of ARB in Patients with Hypertension and Moderate Chronic Kidney Disease in Primary Care Settings(PJ054,Kidney/Renal Circulation/CKD 3 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation
- CLINICAL RESULTS OF ENDOSCOPIC HEMOSTASIS USING A SHORT TRANSPARENT HOOD AND SHORT HEMOCLIPS FOR NON-VARICEAL UPPER GASTROINTESTINAL BLEEDING
- Autoimmune Hepatitis Associated with Pulmonary Arterial Hypertension
- Effect of Education through a Periodic Newsletter on Persistence with Antihypertensive Therapy
- Novel pathophysiological concepts of inflammatory bowel disease
- Therapeutic strategies for functional dyspepsia and the introduction of the Rome III classification
- Update on the pathophysiology of inflammatory bowel disease
- Trends in Blood Pressure Control in Hypertensive Patients with Diabetes Mellitus in Japan
- Cost-Effectiveness Analysis : Controlled-Release Nifedipine and Valsartan Combination Therapy in Patients with Essential Hypertension : The Adalat CR and Valsartan Cost-Effectiveness Combination (ADVANCE-Combi) Study
- Cost-Utility Analysis of Antihypertensive Combination Therapy in Japan by a Monte Carlo Simulation Model
- Coping strategy when patients with quiescent Crohn's disease recognize that their conditions are worsening
- Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis
- Animal models of inflammatory bowel disease
- Does Helicobacter pylori attack ghrelin-producing cells?
- Does an elemental diet affect operation and/or recurrence rate in Crohn's disease in Japan?
- Is fish oil (n-3 fatty acids) effective for the maintenance of remission in Crohn's disease?
- Immunoregulatory therapies targeting inflammatory cytokines against inflammatory bowel disease
- Enhanced ghrelin expression and subsequent acid secretion in mice with genetic H_2-receptor knockout
- Molecular Biological Studies of the Pathogenesis in Inflammatory Bowel Disease
- Controlled Release Nifedipine and Valsartan Combination Therapy in Patients with Essential Hypertension : The Adalat CR and Valsartan Cost-Effectiveness Combination (ADVANCE-Combi) Study
- Do immunosuppressants really work as maintenance therapy after the achievement of remission of severe ulcerative colitis?
- Biological therapies for inflammatory bowel disease
- Sugar microanalysis by HPLC with benzoylation : Improvement via introduction of a C-8 cartridge and a high efficiency ODS column
- Potential Errors Resulting from Sex and Age Difference in Assessing Family History of Coronary Heart Disease
- Importance of Sex and Age Factor in Assessing Family History of Stroke
- Importance of Age Factor in Assessing Family History of Coronary Heart Disease
- Genetics of inflammatory bowel disease in Japan
- Advanced Pancreatic Cancer Successfully Treated with Biweekly Low-Dose Gemcitabine
- Diagnosis of toxic shock syndrome by two different systems : clinical criteria and monitoring of TSST-1-reactive T cells
- Intestinal macrophage, "a double-edged sword" for homeostasis and inflammation in the gut
- Target biopsy or step biopsy? Optimal surveillance for ulcerative colitis : a Japanese nationwide randomized controlled trial
- Overexpression of apelin receptor (APJ/AGTRL1) on hepatic stellate cells and sinusoidal angiogenesis in human cirrhotic liver
- OJ-083 Controlled Release Nifedipine and Valsartan Combination Therapy in Patients with Essential Hypertension : ADVANCE Combi Study(Hypertension, clinical-3 (H) OJ14,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japan
- Regulation of Aldosterone Secretion by a New Aldosterone Stimulating Factor : THE 11th CONFERENCE ON THE PATHOGENESIS OF HYPERTENSION
- PJ-526 Cost-Effectiveness Analysis of Controlled Release Nifedipine and Valsartan Combination Therapy in Patients with Essential Hypertension : ADVANCE Combi Study(Cost-health care system (H) PJ89,Poster Session (Japanese),The 70th Anniversary Annual Scie
- PE-377 Targeted Administration of Doxazosin could Decrease HsCRP and Prevent the Progression of IMT in Hypertensive Patient with Morning Surge(Atherosclerosis, clinical-08, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- A Novel Approach to Assessing Family History in the Prevention of Coronary Heart Disease
- Role of High Molecular Weight Adiponectin in the Correlation Between Higher B-type Natriuretic Peptide Level and Accumulation of Metabolic Syndrome-Related Factors-Examination in Japanese Mass Screening
- Influence of Nighttime Bathing on Evening Home Blood Pressure Measurements : How Long Should the Interval Be after Bathing?
- Reproducibility of Masked Hypertension Determined from Morning and Evening Home Blood Pressure Measurements over a 6-Month Period
- Guidelines for the Clinical Use of 24 Hour Ambulatory Blood Pressure Monitoring (ABPM) (JCS 2010) : Digest Version
- Optimal Combination of Effective ANtihypertensives (OCEAN) study : a prospective, randomized, open-label, blinded endpoint trial-rationale, design and results of a pilot study in Japan
- Usefulness of Measuring Serum High-molecular-weight Adiponectin Level by Recently-developed Chemiluminescence Enzyme Immunoassay in Health Check-up
- A Case of Intestinal Behçet's Disease Treated with Infliximab Monotherapy Who Successfully Maintained Clinical Remission and Complete Mucosal Healing for Six Years
- Insulin Resistance and Hypertension in Adolescents and Adults
- Microscopic Colitis with Granuloma Which Responded to Steroid Therapy
- Effects of Excessive Ethanol Consumption on the Diagnosis of the Metabolic Syndrome Using Its Clinical Diagnostic Criteria
- Usefulness of Measuring Serum High-molecular-weight Adiponectin Level by Recently-developed Chemiluminescence Enzyme Immunoassay in Health Check-up
- Enhanced expressions of apelin on proliferative hepatic arterial capillaries in human cirrhotic liver