Initial and Long-Term Outcomes of Sirolimus-Eluting Stents for Calcified Lesions Compared With Bare-Metal Stents
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概要
- 論文の詳細を見る
The aim of this study was to compare the initial and long-term outcomes of sirolimus-eluting stents (SES) and bare-metal stents (BMS) in patients with calcified lesions without performing rotational atherectomy. The subjects were 79 consecutive lesions (38 in the SES group and 41 in the BMS group) which were confirmed to have superficially calcified lesions by intravascular ultrasound. In all lesions, the stent was implanted after predilatation with a balloon. The patient characteristics were not different between the 2 groups. All procedures were successfully performed in both groups. Vessel area was significantly smaller in the SES group than in the BMS group (11.01 ± 3.88 mm2 versus 13.08 ± 3.49 mm2, P < 0.005), as was the lumen area (5.41 ± 2.31mm2 versus 6.48 ± 2.04 mm2, P < 0.005). Minimum stent area was significantly smaller in the SES group than in the BMS group (5.61 ± 1.54 mm2 versus 6.69 ± 1.74 mm2, P < 0.01). In cases in whom angiographic follow-ups were performed, the late loss was significantly smaller in the SES group than in the BMS group (0.19 ± 0.49 mm versus 0.76 ± 0.48 mm, P < 0.001). The restenosis rate was significantly lower in the SES group than in the BMS group (8.8% versus 33.3%, P < 0.05) and the TLR rate tended to be lower in the SES group (7.9% versus 19.5%). Stent thrombosis was not observed in either group. The results suggest that SES are more effective than BMS and can be used safely when treating calcified lesions if predilatation with a balloon is possible.
著者
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Onoda Satoru
Division of Cardiology, Saitama Cardiovascular and Respiratory Center
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Taniguchi Masayuki
Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine
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Mochizuki Seibu
Division Of Cardiology Department Of Internal Medicine Jikei Univerisity School Of Medicine
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Seo Atsushi
Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine
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Koga Atsushi
Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine
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Fujii Takuro
Division Of Cardiology Department Of Internal Medicine The Jukei University School Of Medicine Daisa
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Inoue Terumasa
Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine
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Kurusu Takashi
Division Of Cardiology Jikei University School Of Medicine
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Takikawa Kazutoshi
Division Of Cardiology Jikei University School Of Medicine
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Tanaka Yasuyuki
Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine
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Shibata Takahiro
Division Of Cardiology Department Of Internal Medicine Jikei University School Of Medicine
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Chin Keiichi
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, Daisan Hospital
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Taniguchi Masayuki
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, Daisan Hospital
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Inoue Terumasa
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, Daisan Hospital
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Koga Atsushi
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, Daisan Hospital
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Onoda Satoru
Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, Daisan Hospital
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