Coexistence of Familial Hypertrophic Cardiomyopathy and Vasospastic Angina Pectoris in Two Brothers
スポンサーリンク
概要
- 論文の詳細を見る
Two brothers had familial hypertrophic cardiomyopathy and vasospastic angina pectoris concurrently. Their family history showed that one of their sisters had hypertrophic cardiomyopathy and another brother died suddenly at age 52. The clinical diagnosis of hypertrophic cardiomyopathy was confirmed by an echocardiogram and left ventriculo-graphy. They had typical chest pain at rest, and a significant vasospasm of coronary arteries with chest pain and obvious ST-T changes in the elctrocardiograms was provoked by intracoronary injection of acetylcholine in both patients. The administration of a calcium antagonist and nitrate was effective for ameliorating chest pain with no cardiovascular events during the follow up period of more than 3 years. Although underlying pathophysiologic abnormalities of familial hypertrophic cardiomyopathy and vasospastic angina pectoris are considered to be transmitted genetically, the genetic backgrounds of these cases remain to be clarified.<br>
著者
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Seto Shinji
Department Of Cardiovascular Medicine Course Of Medical And Dental Sciences Graduate School Of Biome
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Yano Katsusuke
Department Of Cardiology Nagasaki University Hospital
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Kawano Hiroaki
Department Cardiovascular Medicine Kumamoto University:division Of Intensive Care Unit Kumamoto Univ
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Hirano Hisataka
Department of Cardiology, Nagasaki Citizens Hospital
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Suzuki Nobuaki
Department Of Cardiology Japanese Red Cross Nagasaki Genbaku Hospital
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Hirano Hisataka
Department of Cardiovascular Medicine, Course of Medical and Dental Sciences, Graduate School of Biomedical Sciences, Nagasaki University
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Koide Yuji
Department of Cardiovascular Medicine, Course of Medical and Dental Sciences, Graduate School of Biomedical Sciences, Nagasaki University
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KOIDE Yuji
Department of Agricultural Chemistry, Faculty of Agriculture, Hokkaido University
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Sato Osami
Department of Cardiovascular Medicine, Course of Medical and Dental Sciences, Graduate School of Biomedical Sciences, Nagasaki University
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Suzuki Nobuaki
Department of Cardiovascular Medicine, Course of Medical and Dental Sciences, Graduate School of Biomedical Sciences, Nagasaki University
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