肝細胞癌に対する経皮的ラジオ波焼灼療法と肝切除の治療成績の比較検討

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102 patients with solitary hepatocellular carcinoma (HCC) less than 3 cm in diameter were enrolled in this study. Among these patients, 77 patients were treated by percutaneous radiofrequency ablation (RFA), and the others were subjected to hepatic resection. The cumulative 1-, 2- and 3-years recurrence rate in the RFA group was 20.5, 43.1 and 67.7 %, respectively, while 16.0, 33.3 and 53.6 % in the hepatic resection group. The cumulative 1-, 2-, 3- and 4-years survival rate in the RFA group was 98.6, 96.2, 79.1 and 79.1 %, respectively, while 96.0, 96.0, 91.4 and 85.7 % in the hepatic resection group. Multivariate analysis showed no difference between these groups concerning both recurrence and survival after therapy. We believe that RFA is more desirable therapy for small HCC, because it is important to reserve hepatic function in patients with HCC in whom recurrence after therapy is frequent due to underlying liver disease.
特定非営利活動法人 Microwave Surgery研究会の論文