Quercetin and the Glucosides Inhibit Nitration of a Salivary Component 4-Hydroxyphenylacetic Acid Catalyzed by Salivary Polymorphonuclear Leukocytes
スポンサーリンク
概要
- 論文の詳細を見る
Mixed whole human saliva contains 4-hydroxyphenylacetic acid (HPA), nitrite and polymorphonuclear leukocytes. Salivary leukocytes nitrated HPA to 4-hydroxy-3-nitrophenylacetic acid in the presence of nitrite, and phorbol myristate acetate stimulated the nitration. Quercetin and the glucosides, which are found in the oral cavity after ingestion of quercetin-rich foods, inhibited the leukocyte-dependent nitration. The inhibition by quercetin and the glucosides was in part due to the flavonol-dependent scavenging of nitrogen dioxide which was formed by myeloperoxidase-dependent oxidation of nitrite. Salivary components, SCN and uric acid, also inhibited the nitration. The above re-sults suggest that quercetin can cooperate with SCN and uric acid to prevent nitration in the oral cavity.
- 社団法人 日本食品科学工学会の論文
- 2003-11-01
著者
-
TAKAHAMA Umeo
Kyushu Dental University
-
Hirota Sachiko
Department Of Nutritional Science Kyushu Women's University
-
Takahama Umeo
Kyushu Dental College
関連論文
- Oxidation of Quercetin by Salivary Components II. Effects of Quercetin on Reactive Oxygen Metabolism by Salivary Polymorphonuclear Leukocytes
- Oxidation of Quercetin by Salivary Components I. Salivary Peroxidase-Dependent Oxidation of Quercetin and Characterization of the Oxidation Products
- Quercetin Glucosides are Hydrolyzed to Quercetin in Human Oral Cavity to Participate in Peroxidase-Dependent Scavenging of Hydrogen Peroxide
- Flavonoids and Some Other Phenolics as Substrates of Peroxidase: Physiological Significance of the Redox Reactions
- Effects of Ascorbate on the Oxidation of Derivatives of Hydroxycinnamic Acid and the Mechanism of Oxidation of Sinapic Acid by Cell Wall-Bound Peroxidases : GENES STRUCTURE AND EXPRESSION
- A Possible Mechanism for the Oxidation of Sinapyl Alcohol by Peroxidase-Dependent Reactions in the Apoplast: Enhancement of the Oxidation by Hydroxycinnamic Acids and Components of the Apoplast
- Detection of Monodehydroascorbic Acid Radical in Sulfite-Treated Leaves and Mechanism of its Formation
- AGE-DEPENDENT CHANGES IN LEVELS OF ASCORBIC ACID AND CHLOROGENIC ACID, AND ACTIVITIES OF PEROXIDASE AND SUPEROXIDE DISMUTASE IN THE APOPLAST OF TOBACCO LEAVES
- Age-Dependent Changes in Levels of Ascorbic Acid and Chlorogenic Acid, and Activities of Peroxidase and Superoxide Dismutase in the Apoplast of Tobacco leaves : Mechanism of the Oxidation of Chlorogenic Acid in the Apoplast
- 3, 4-Dihydroxyphenylalanine Is Oxidized by Phenoxyl Radicals of Hydroxycinnamic Acid Esters in Leaves of Vicia faba L.
- PRODUCTION OF PHENOLICS AND ACTIVE OXYGEN SPECIES AS ANTIMICROBIAL COMPOUNDS DURING MATURING OF ONIONSCALES
- THE MECHANISM OF PEROXIDASE-DEPENDENT OXIDATION OF 3, 4-DIHYDROXYPHENYLALANINE IN MESOPHYLL CELLS OF Vicia Faba
- Phenolic Components of Brown Scales of Onion Bulbs Produce Hydrogen Peroxide by Autooxidation
- Free radicals produced by the oxidation of gallic acid and catechin derivatives
- Enhancement of Peroxidase-Dependent Oxidation of Sinapyl Alcohol by an Apoplastic Component, 4-Coumaric Acid Ester Isolated from Epicotyls of Vigna angularis L.
- Distribution of Flavonols and Enzymes Participating in the Metabolism in Onion Bulbs : Mechanism of Accumulation of Quercetin and Its Glucosides in the Abaxial Epidermis
- Quercetin and the Glucosides Inhibit Nitration of a Salivary Component 4-Hydroxyphenylacetic Acid Catalyzed by Salivary Polymorphonuclear Leukocytes
- Deglucosidation of Quercetin Glucosides to the Aglycone and Formation of Antifungal Agents by Peroxidase-Dependent Oxidation of Quercetin on Browning of Onion Scales
- QUERCETIN IS A NATURAL ELECTRON DONOR TO PEROXIDASE IN ONION BULBS
- Oxidation of Quercetin by Carotenoid Radical Generated in Illuminated Spinach Chloroplasts : The Effect of Ascorbate on Quercetin Oxidation
- Generation of Hydroxyl Radical in Isolated Pea Root Cell Wall, and the Role of Cell Wall-Bound Peroxidase, Mn-SOD and Phenolics in Their Production