Studies on chemical induction of chromosomal aberrations in postcopulation germ cells and zygotes of female mice. II. Induction of heritable translocations.:II. Induction of heritable translocations
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概要
- 論文の詳細を見る
The induction of heritable translocations with chemicals in postcopulation germ cells of female mice was investigated. In the methyl methanesulfonate (MMS)-treated group (100mg/kg), 14 partially sterile and 5 sterile males out of 118 F1 male progeny were found. In contrast, in the mitomycin C (MC)- treated group (3mg/kg and 4mg/kg) the frequencies were low. These results indicate that the yield of heritable translocations parallels the formation of chromosome-type aberrations at the first cleavage reported previously.
- 日本遺伝学会の論文
著者
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IWAHARA Shigeo
Laboratory of Genetics, Hatano Research Institute
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WAKISAKA Ichiro
Department of Public Health, Faculty of Medicine, Kagoshima University
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Wakisaka Ichiro
Department Of Environmental Sciences Division National Institute For Environmental Studies
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Hashimoto Koroku
Laboratory Of Pharmacology Hatano Research Institute Food & Drug Safety Center
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Tanaka Noriho
Laboratory Of Cell Carcinogenesis Division Of Alternative Research Food And Drug Safety Center
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KATOH Motoe
Laboratory of Genetic Toxicology, Hatano Research Institute, Food and Drug Safety Center
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- Studies on chemical induction of chromosomal aberrations in postcopulation germ cells and zygotes of female mice. II. Induction of heritable translocations.:II. Induction of heritable translocations
- Studies on chemical induction of chromosomal aberrations in postcopulation germ cells and zygotes of female mice. I. Comparative studies on the frequency of first-cleavage chromosomal aberrations and dominant-lethal mutations.:I. Comparative studies on th