Isopropyl methanesulfonateの雄マウス投与による1細胞期胚染色体異常と優性致死誘発との関連性〔英文〕

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概要

• 論文の詳細を見る

• A high dose (200mg/kg) of isopropyl methanesulfonate (iPMS) induced a high frequency of postimplantation loss in postmeiotic male germ cell stages, but the frequency of eggs with chromosome aberrations observed at the first cleavage metaphases was very low. Therefore, we suggest that the postimplantation loss in dominant lethal mutations induced by iPMS is mainly attributable to the alteration of subchromosome material at the first cleavage metaphases.

• 日本遺伝学会の論文

著者

• 加藤 基恵

  Laboratory of Genetics, Hatano Research Institute

• 岩原 繁雄

  Laboratory of Genetics, Hatano Research Institute

• KATOH Motoe

  Laboratory of Genetics, Hatano Research Institute

• IWAHARA Shigeo

  Laboratory of Genetics, Hatano Research Institute

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• マウス雄生殖細胞における不定期DNA合成〔英文〕
• Isopropyl methanesulfonateの雄マウス投与による1細胞期胚染色体異常と優性致死誘発との関連性〔英文〕
• MUTAGENICITY TESTING OF ST-FILM WITH THE AMES TEST, CHROMOSOME TEST IN VITRO AND MICRONUCLEUS TEST IN FEMALE MICE
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• Studies on chemical induction of chromosomal aberrations in postcopulation germ cells and zygotes of female mice. II. Induction of heritable translocations.:II. Induction of heritable translocations

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