Synthesis of ω-Chain Shortened Prostaglandins and Their Six-membered Ring Analogs

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概要

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• Prostaglandin E1 analogs 5a and 5b, having methyl and ethyl groups as the co-chain, were synthesized by a two-step alkylation system of diethyl 3-oxoglutarate (1) and their six-membered ring analogs 8a and 8b also derived from the first alkylation product 2 via a Michael reaction.

• 社団法人 日本農芸化学会の論文

著者

• Doi Kiyoshi

  Department Of Cardiovascular Surgery Kyoto Prefectural University Of Medicine

• Hayashi Shuichi

  Department Of Applied Chemistry. Faculty Of Engineering Toyama University

• Naoshima Yoshinobu

  Department Of Agricultural Chemistry University Of Osaka Prefecture

• TAKEHI Takayoshi

  Department of Chemistry, Faculty of Science, Okayama University of Science

• WAKABAYASHI Shoji

  Department of Chemistry, Faculty of Science, Okayama University of Science

• DOI Kiyoshi

  Department of Chemistry, Faculty of Science, Okayama University of Science

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