Fungal Transformation of the Antifungal Isoflavone Luteone
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概要
- 論文の詳細を見る
An antifungal isoflavone, luteone [5, 7, 2′, 4′-tetrahydroxy-6-(3, 3-diniethylallyl)isoflavone] is metabolised by cultures of Aspergillus flavus and Botrytis cinerea into 2″, 3″-dihydro-3″-hydroxyluteone (AF- 1), 2″, 3″-dihydrodihydroxyluteone, a dihydrofuranoisoflavone (BG-1) and a dihydropyranoisoflavone. The structures of the metabolites were elucidated by physico-chemical and chemical procedures. The major metabolites, AF-1 and BC-1 are much less toxic than luteone against Cladosporium herbarum. The possible metabolic pathways are briefly discussed.
- 社団法人 日本農芸化学会の論文
著者
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Tahara Satoshi
Department Of Agricultural Chemistry Faculty Of Agriculture Hokkaido University
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Mizutani Junya
Department Of Agricultural Chemistry Faculty Of Agriculture Hokkaido University
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INGHAM John
Phytochemical Unit, Department of Botany, University of Reading
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Nakahara Shiro
Department Of Cardiology Dokkyo Medical University Koshigaya Hospital
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