[症例報告]Sarcomatoid carcinoma (so-called carcinosarcoma) of the gallbladder : A case report and review of the literature

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The case of a rare, peculiar tumor (sarcomatoid carcinoma, carcinosarcoma) in the gallbladder of an 82-year-old woman is herein described. The patient was admitted with right upper quadrant tenderness and mass. On admission, abdominal imaging modalities demonstrated a 10 cm-solid mass in the right upper quadrant with nonspecific features similar to those of carcinoma of the gallbladder. She was diagnosed to have carcinoma of the gallbladder, and thereafter underwent an extirpation of the tumor together with a cholecystectomy and partial transverse colectomy. The tumor was relatively circumscribed with invasion into the transverse mesocolon, and measured 12cm in greatest dimension. On bisection, the tumor showed a massive intraluminal polypoid and exophytic growth in the gallbladder with a solid, gray-color, and fibrous appearance. Histologically, the tumor was composed of three different tumor cell types (tubular adenocarcinoma, giant cell and spindle cell types). The giant cell-type cells occupied the largest part of the tumor and were infiltrated with lymphoid cells and leukocytes. Immunohistochemically, tubular adenocarcinoma was positive for cytokeratin while the remaining two components were negative for cytokeratin and vimentin. One month later, the patient developed local recurrence of the tumor at the primary site. The tumor grew rapidly and aggressively. As a result, she died 7 months after surgery.
琉球医学会の論文
1999-00-00