[原著］沖縄におけるHTLV-Iキャリア妊婦の実態とWestern blot法によるIgM抗体の解析および児のキャリア化について

概要

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The overall prevalence of HTLV-I antibodies in pregnant women was 6.5% in Okinawa. Antibody-positive rate was significantly higher in multiparous patients than in primiparous patients (P<0.05). Although breast milk feeding is considered to be the primary route of the mother-to-child transmission of HTLV-I, precise mechanisms of the virus transmission have not been elucidated. We surveyed the titer of the HTLV-I antibody in carrier mothers and analysed the immunoglobulin classes. The HTLV-I antibodies of IgM class were detected in 18 of 63 carrier mothers (28.6%). The mothers having the IgM antibodies showed relatively higher titer of antibodies to HTLV-I. However, the seroconversion rate in children born from these mothers was not significantly high.
琉球医学会,Ryukyu Medical Associationの論文